Imai Junta, Sato Katsuhisa, Takahashi Masanobu, Ojima Toshiaki, Kuroki Michio, Iijima Katsunori, Kamiya Takayoshi, Kashimura Junya, Ikeya Shinichi, Endo Itaru, Saito Yasutoshi
Dept. of Gastroenterology, Iwaki Kyoritu General Hospital.
Gan To Kagaku Ryoho. 2002 Nov;29(11):2001-4.
The patient was a 68-year-old woman. She was referred to our hospital because of advanced gastric cancer. Endoscopic examination showed that the tumor was located in the Subcardia, with its oral margin invading the esophagus. Histologic examination of biopsy specimen led to a diagnosis of moderately to poorly differentiated adenocarcinoma. Apparent lymph node swellings (No. 7, No. 11) on enhanced CT examination indicated the metastasis of the gastric cancer. Consulting with her family, we decided to treat the cancer with chemotherapy using the peroral carcinostatic "UFT", and started it on November 18, 1997. Follow-up endoscopic examination confirmed that the tumor was reduced in size immediately after starting chemotherapy, and then finally disappeared on December 10, 1999. Since then, there has been no recurrence of the tumor. This is a rare case of gastric cancer showing complete response to chemotherapy using a peroral carcinosatatic alone.
该患者为一名68岁女性。她因晚期胃癌被转诊至我院。内镜检查显示肿瘤位于贲门下方，其近端边缘侵犯食管。活检标本的组织学检查诊断为中分化至低分化腺癌。增强CT检查显示明显的淋巴结肿大（第7组、第11组），提示胃癌转移。与她的家人商议后，我们决定使用口服抗癌药“优福定”进行化疗，于1997年11月18日开始治疗。随访内镜检查证实，化疗开始后肿瘤立即缩小，最终于1999年12月10日消失。此后，肿瘤未再复发。这是一例罕见的仅使用口服抗癌药化疗即显示完全缓解的胃癌病例。
