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一名髓母细胞瘤患儿发生迟发性辐射诱导性血管病变和中风。

Late-onset radiation-induced vasculopathy and stroke in a child with medulloblastoma.

作者信息

Bansal Lalit R, Belair Jeffrey, Cummings Dana, Zuccoli Giulio

机构信息

Division of Child Neurology, Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pittsburgh, PA, USA

Department of Radiology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

出版信息

J Child Neurol. 2015 May;30(6):800-2. doi: 10.1177/0883073814538501. Epub 2014 Jul 10.

DOI:10.1177/0883073814538501
PMID:25015672
Abstract

We report a case of a 15-year-old boy who presented to our institution with left-sided weakness and slurred speech. He had a history of medulloblastoma diagnosed at 3 years of age, status postsurgical resection and craniospinal radiation. Magnetic resonance imaging (MRI) of brain revealed a right paramedian pontine infarction, suspected secondary to late-onset radiation-induced vasculopathy of the vertebrobasilar system. Radiation to the brain is associated with increased incidence of ischemic stroke. Clinicians should have a high index of suspicion for stroke when these patients present with new neurologic symptoms.

摘要

我们报告一例15岁男孩,他因左侧肢体无力和言语不清前来我院就诊。他在3岁时被诊断为髓母细胞瘤,接受过手术切除和颅脊髓放疗。脑部磁共振成像(MRI)显示右侧脑桥旁正中梗死,怀疑继发于迟发性椎基底系统放射性血管病。脑部放疗与缺血性卒中发生率增加有关。当这些患者出现新的神经系统症状时,临床医生应高度怀疑卒中。

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