Department of Internal Medicine, University Hospital of Salamanca-IBSAL, Salamanca, Spain.
Department of Orthopedic Surgery, Spain.
J Arthroplasty. 2014 Oct;29(10):2016-20. doi: 10.1016/j.arth.2014.06.005. Epub 2014 Jun 9.
The aim of our study was to determine the potential influence of blood transfusion and the length of storage of packed red blood cells (RBC) on prosthetic joint infection after primary knee arthroplasty. From November 2007 to November 2009, all variables potentially associated with deep infection were registered in 1331 consecutive patients who underwent total knee arthroplasty. Infection was diagnosed in 32 (2.4%) patients. After adjusting for important variables, blood transfusion with RBCs stored >14days was the strongest predictive factor for prosthetic joint infection within 90days after primary knee arthroplasty (OR: 5.9, 95% CI: 2.6-13.2, P < 0.001). Blood saving techniques are desirable to reduce perioperative blood transfusion.
我们的研究目的是确定输血和储存时间对初次膝关节置换术后人工关节感染的潜在影响。2007 年 11 月至 2009 年 11 月，我们对 1331 例连续接受全膝关节置换术的患者记录了所有可能与深部感染相关的变量。32 例（2.4%）患者被诊断为感染。在调整了重要变量后，输血和储存时间超过 14 天是初次膝关节置换术后 90 天内发生人工关节感染的最强预测因素（OR：5.9，95%CI：2.6-13.2，P < 0.001）。为了减少围手术期输血，有必要采用血液保存技术。
