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J Bone Joint Surg Am. 2014 Sep 17;96(18):e155. doi: 10.2106/JBJS.M.00825.
2
Joint replacement registries in the United States: a new paradigm.美国的关节置换登记处:一种新范式。
J Bone Joint Surg Am. 2014 Sep 17;96(18):1567-9. doi: 10.2106/JBJS.N.00641.
3
Length of storage of transfused red blood cells and risk of prosthetic joint infection after primary knee arthroplasty.输红细胞储存时间与初次膝关节置换术后人工关节感染的风险。
J Arthroplasty. 2014 Oct;29(10):2016-20. doi: 10.1016/j.arth.2014.06.005. Epub 2014 Jun 9.
4
National trends in the utilization of blood transfusions in total hip and knee arthroplasty.全髋关节和膝关节置换术输血利用的国家趋势。
J Arthroplasty. 2014 Oct;29(10):1932-7. doi: 10.1016/j.arth.2014.04.029. Epub 2014 Apr 26.
5
Impact of the economic downturn on total joint replacement demand in the United States: updated projections to 2021.美国经济衰退对全关节置换需求的影响:更新至 2021 年的预测。
J Bone Joint Surg Am. 2014 Apr 16;96(8):624-30. doi: 10.2106/JBJS.M.00285.
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Thirty-day readmission following total hip and knee arthroplasty - a preliminary single institution predictive model.全髋关节和膝关节置换术后 30 天再入院 - 初步的单机构预测模型。
J Arthroplasty. 2014 Aug;29(8):1532-8. doi: 10.1016/j.arth.2014.02.030. Epub 2014 Mar 4.
7
Health care-associated infection after red blood cell transfusion: a systematic review and meta-analysis.输血相关的医疗保健相关性感染:系统评价和荟萃分析。
JAMA. 2014 Apr 2;311(13):1317-26. doi: 10.1001/jama.2014.2726.
8
Prevalence of doctor-diagnosed arthritis and arthritis-attributable activity limitation--United States, 2010-2012.2010-2012 年美国医生诊断的关节炎及与关节炎相关的活动受限患病率。
MMWR Morb Mortal Wkly Rep. 2013 Nov 8;62(44):869-73.
9
Blood utilization after primary total joint arthroplasty in a large hospital network.大型医院网络中初次全关节置换术后的血液利用。
HSS J. 2013 Jul;9(2):123-8. doi: 10.1007/s11420-013-9327-y. Epub 2013 Jun 21.
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关节置换登记系统能否有助于减少初次全关节置换术中的输血?一项质量改进计划。

Can an Arthroplasty Registry Help Decrease Transfusions in Primary Total Joint Replacement? A Quality Initiative.

作者信息

Markel David C, Allen Mark W, Zappa Nicole M

机构信息

Providence Hospital and Medical Centers and The CORE Institute, 22250 Providence Drive, Suite #401, Southfield, MI, 48075, USA.

St John Macomb-Oakland Hospital, Oakland Center, Madison Heights, MI, USA.

出版信息

Clin Orthop Relat Res. 2016 Jan;474(1):126-31. doi: 10.1007/s11999-015-4470-z.

DOI:10.1007/s11999-015-4470-z
PMID:26215083
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4686507/
Abstract

BACKGROUND

Standardized care plans are effective at controlling cost and quality. Registries provide insights into quality and outcomes for use of implants, but most registries do not combine implant and care quality data. In 2012, several Michigan area hospitals and a major insurance provider formed a voluntary statewide total joint database/registry, the Michigan Arthroplasty Registry Collaborative Quality Initiative (MARCQI), to collect procedural, hospital, discharge, and readmission data. Noting substantial variation in transfusion practices after total joint arthroplasty (TJA) in our institutions, we used these prospectively collected data to examine whether awareness and education of the American Association of Blood Banks' (AABB) transfusion guidelines would result in decreased transfusions.

QUESTIONS/PURPOSES: (1) Can an established arthroplasty registry help implement a quality initiative (QI) designed to decrease the proportion of transfused postoperative patients undergoing TJA? (2) Do data-driven transfusion protocols decrease length of stay without increasing ischemic complications (myocardial infarctions and cerebrovascular accidents)? (3) Are decreased transfusion proportions associated with decreased readmissions, nonischemic morbidity (including deep vein thrombosis and deep prosthetic infection), and mortality in postoperative patients who had undergone TJA?

METHODS

After reviewing data from the recently established MARCQI registry, the orthopaedic department noticed many discrepancies and practice variances regarding blood transfusions among their providers. In October 2013, a QI was implemented to raise awareness of the discrepancies and education about the AABB guidelines was presented at the monthly orthopaedic service line meeting. A total of 1872 TJA cases were reviewed; 50 were excluded for incomplete data and two for intraoperative transfusions for the period before education (May 2012 to June 2013, n = 1240) and after education (November 2013 to April 2014, n = 580). Data collected included gender, age, length of stay, body mass index, preoperative hemoglobin level, lowest postoperative hemoglobin level during admission, transfusion status, number of units transfused, ischemic and nonischemic morbidity, hospital readmissions within 90 days, and mortality. Pre- and post-QI transfusion proportions were calculated. Chi-square test, Student's t-test, and a multivariate analysis were performed to compare differences in transfusion proportions for patients with a postoperative hemoglobin ≥ 8 g/dL.

RESULTS

Overall, the percentage of patients transfused with a postoperative hemoglobin ≥ 8 g/dL decreased 80% (6.5% [71 of 1092] versus 1.3% [seven of 538]; odds ratio, 5.3; 95% confidence interval, 2.4-11.6; p < 0.001) after the educational intervention. Before education, 16% (195 of 1240) of all patients undergoing TJA were transfused, whereas 6.5% (71 of 1092) were outside recommended AABB guidelines (hemoglobin ≥ 8 g/dL). In the 6 months after QI initiation, overall transfusions decreased to 6% (35 of 580) with 1.3% (seven of 538) having a hemoglobin ≥ 8 g/dL. The mean length of stay for nontransfused patients was shorter (2.4 days ± 0.9 versus 3.3 days ± 1.1, p < 0.001) and ischemic complications did not differ between groups (0.32% [four of 1240] versus 0.34% [two of 580], p = 0.61). Before and after education, neither the number of readmissions (5.4% [67 of 1240] versus 4.7% [27 of 580], p = 0.50) nor morbidity (3.6% [45 of 1240] versus 2.4% [14 of 580], p = 0.17) differed between time periods. There were no deaths.

CONCLUSIONS

Simple education and awareness of quality practices drive safety and compliance. The impact can be immediate and lasting. Arthroplasty registries that combine procedural and care quality data are vital and may be used for important data-driven QIs.

LEVEL OF EVIDENCE

Level III, therapeutic study.

摘要

背景

标准化护理计划在控制成本和质量方面很有效。登记处能提供有关植入物使用的质量和结果的见解,但大多数登记处并未将植入物和护理质量数据结合起来。2012年,密歇根州的几家医院和一家主要保险提供商组建了一个全州范围的自愿性全关节数据库/登记处,即密歇根关节成形术登记协作质量倡议(MARCQI),以收集手术、医院、出院和再入院数据。注意到我们机构中全关节置换术(TJA)后输血做法存在很大差异,我们利用这些前瞻性收集的数据来研究美国血库协会(AABB)输血指南的宣传和教育是否会减少输血。

问题/目的:(1)一个已建立的关节成形术登记处能否帮助实施一项旨在降低接受TJA的术后输血患者比例的质量改进(QI)措施?(2)数据驱动的输血方案在不增加缺血性并发症(心肌梗死和脑血管意外)的情况下是否会缩短住院时间?(3)输血比例降低是否与接受TJA的术后患者的再入院率降低、非缺血性发病率(包括深静脉血栓形成和深部假体感染)及死亡率降低相关?

方法

在审查了最近建立的MARCQI登记处的数据后,骨科发现其医疗服务提供者之间在输血方面存在许多差异和做法差异。2013年10月,实施了一项QI措施以提高对差异的认识,并在每月的骨科服务线会议上介绍了关于AABB指南的教育内容。共审查了1872例TJA病例;50例因数据不完整被排除,2例因教育前时期(2012年5月至2013年6月,n = 1240)和教育后时期(2013年11月至2014年4月,n = 580)的术中输血被排除。收集的数据包括性别、年龄、住院时间、体重指数、术前血红蛋白水平、住院期间术后最低血红蛋白水平、输血状态、输血量、缺血性和非缺血性发病率、90天内的医院再入院情况及死亡率。计算了QI前后的输血比例。进行了卡方检验、学生t检验和多变量分析,以比较术后血红蛋白≥8 g/dL患者的输血比例差异。

结果

总体而言,在教育干预后,术后血红蛋白≥8 g/dL的输血患者百分比下降了80%(6.5%[1092例中的71例]对1.3%[538例中的7例];优势比,5.3;95%置信区间,2.4 - 11.6;p < 0.001)。教育前,所有接受TJA的患者中有16%(1240例中的195例)接受了输血,而6.5%(1092例中的71例)超出了AABB推荐指南(血红蛋白≥8 g/dL)。在QI启动后的6个月内,总体输血率降至6%(580例中的35例),其中血红蛋白≥8 g/dL的为1.3%(538例中的7例)。未输血患者的平均住院时间较短(2.4天±0.9对3.3天±1.1,p < 0.001),且两组间缺血性并发症无差异(0.32%[1240例中的4例]对0.34%[580例中的2例],p = 0.61)。教育前后,再入院次数(5.4%[1240例中的67例]对4.7%[580例中的27例],p = 0.50)和发病率(3.6%[1240例中的45例]对2.4%[580例中的14例],p = 0.17)在不同时期均无差异。无死亡病例。

结论

简单的质量实践教育和意识可推动安全性和合规性。其影响可以是即时且持久的。结合手术和护理质量数据的关节成形术登记处至关重要,可用于重要的数据驱动的QI措施。

证据级别

三级,治疗性研究。