Moore James N, Vandenplas Michel L
Department of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, 501 DW Brooks Drive, Athens, GA 30602, USA; Department of Physiology and Pharmacology, College of Veterinary Medicine, University of Georgia, 501 DW Brooks Drive, Athens, GA 30602, USA.
Ross University School of Veterinary Medicine, PO Box 334, Basseterre, Saint Kitts, West Indies.
Vet Clin North Am Equine Pract. 2014 Aug;30(2):337-51, vii-viii. doi: 10.1016/j.cveq.2014.04.003. Epub 2014 Jun 4.
Some veterinarians describe particularly sick horses or neonatal foals as being endotoxemic, whereas others refer to the same animals as having the systemic inflammatory response syndrome. This article reviews the basis for the use of each of these terms in equine practice, and highlights the mechanisms underlying the response of the horse's innate immune system to key structural components of the microorganisms that initiate these conditions, including how some of those responses differ from other species. Current approaches used to treat horses with these conditions are summarized, and caution advised on extrapolating findings from other species to the horse.
一些兽医将特别患病的马匹或新生马驹描述为内毒素血症，而另一些兽医则将这些动物称为患有全身炎症反应综合征。本文回顾了在马医学实践中使用这两个术语的依据，并强调了马的先天免疫系统对引发这些病症的微生物关键结构成分的反应机制，包括其中一些反应与其他物种的差异。总结了目前用于治疗患有这些病症马匹的方法，并提醒注意不能将其他物种的研究结果外推至马。
