van der Zwan A
Ned Tijdschr Geneeskd. 1989 Jun 17;133(24):1230-2.
From 1986 till 1988, 88 patients received sodium valproate for the first time as a therapy for epilepsy. One of them developed a fine tremor, three a coarse tremor with a cogwheel phenomenon, two developed a full parkinsonian syndrome. All these symptoms in these six patients disappeared completely or nearly completely after changing to another anti-epileptic drug or reducing the dose.
从1986年至1988年，88例患者首次接受丙戊酸钠治疗癫痫。其中1例出现细微震颤，3例出现伴有齿轮现象的粗大震颤，2例出现完全性帕金森综合征。这6例患者在更换为其他抗癫痫药物或减少剂量后，所有这些症状完全或几乎完全消失。
