Severns M L, Kline L M, Epley K M
Product Development Laboratory, American Red Cross Blood Services, Rockville, Md.
Vox Sang. 1989;56(2):87-92. doi: 10.1111/j.1423-0410.1989.tb04956.x.
Automated microplate blood-grouping systems rely on a pair of thresholds to determine whether reactions are positive or negative. The determination of these thresholds is a critical step in the quality control process for automated microplate blood grouping. A simple method has been developed for automatically setting these thresholds. A more sophisticated method, which required substantial computational complexity, was also tried. The more complex method did not perform better than the simple method described here.