Gottlieb Maria Gabriela Valle, Closs Vera Elizabeth, Rosemberg Laura Schlatter, Borges Cristiane Alves, Baptista Rafael Reimann, Tavares Graziela Morgana Silva, Gomes Irenio, Schneider Rodolfo Herberto, Schwanke Carla Helena Augustin
1 Graduate Program of Biomedical Gerontology, Geriatric and Gerontology Institute, Pontifical Catholic University of Rio Grande do Sul , Porto Alegre, Brazil .
Metab Syndr Relat Disord. 2014 Sep;12(7):397-401. doi: 10.1089/met.2014.0012. Epub 2014 Jul 14.
The aging process causes alterations in body composition (decrease in lean mass and increase in fat mass), diminution of functionality (strength, mobility, and physical performance), and an increased prevalence of chronic diseases such as metabolic syndrome and obesity. The aim of this study was to investigate the association of body composition and functionality with metabolic syndrome in the elderly.
A cross-sectional study was conducted in the Outpatient Clinic of the Geriatric Service of Hospital São Lucas of Pontifical Catholic University of Rio Grande do Sul (PUCRS) involving 74 patients (14 males and 60 females). The patients were separated into two groups: Group 1=elderly with metabolic syndrome [through the National Cholesterol Education Program Adult Treatment Panel III (NECP ATP III) criteria; n=34], group 2=elderly without metabolic syndrome (n=40). The variables evaluated included age, gender, body composition (circumferences, skinfold thickness, BMI, muscle and fat thickness and muscle mass), functional variables [hand grip strength, Timed Up and Go Test (TUGT), and Sit-to-Stand Test].
The results showed that elderly individuals with metabolic syndrome had a higher mean of the anthropometric measures (except abdominal skinfold thickness) compared to subjects without metabolic syndrome (P<0.005). We observed significant differences for muscle mass index (higher, P=0.029), TUGT (longer time, P=0.008), and hand grip strength (lower, P=0.015) in elderly with metabolic syndrome compared with subjects without metabolic syndrome. However, when these variables were adjusted for gender, age, and body mass index (BMI), none showed a significant association with metabolic syndrome.
We did not observe associations among metabolic syndrome, body composition, and functionality variables.
衰老过程会导致身体成分改变（瘦体重减少，脂肪量增加）、功能下降（力量、活动能力和身体表现），以及代谢综合征和肥胖等慢性疾病的患病率增加。本研究旨在调查老年人身体成分和功能与代谢综合征之间的关联。
在南里奥格兰德天主教大学（PUCRS）圣卢卡斯医院老年科门诊进行了一项横断面研究，涉及74名患者（14名男性和60名女性）。患者被分为两组：第1组=患有代谢综合征的老年人[通过美国国家胆固醇教育计划成人治疗小组第三次报告（NECP ATP III）标准；n = 34]，第2组=无代谢综合征的老年人（n = 40）。评估的变量包括年龄、性别、身体成分（周长、皮褶厚度、体重指数、肌肉和脂肪厚度以及肌肉量）、功能变量[握力、计时起立行走测试（TUGT）和坐立测试]。
结果显示，与无代谢综合征的受试者相比，患有代谢综合征的老年人人体测量指标的平均值更高（腹部皮褶厚度除外）（P < 0.005）。我们观察到，与无代谢综合征的受试者相比，患有代谢综合征的老年人的肌肉量指数（更高，P = 0.029）、TUGT（时间更长，P = 0.008）和握力（更低，P = 0.015）存在显著差异。然而，当对这些变量进行性别、年龄和体重指数（BMI）调整后，没有一个变量与代谢综合征显示出显著关联。
我们未观察到代谢综合征、身体成分和功能变量之间存在关联。
