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绿茶漱口水在智齿拔除术后疼痛控制中的有效性:双盲随机临床试验。

Effectiveness of green tea mouthwash in postoperative pain control following surgical removal of impacted third molars: double blind randomized clinical trial.

出版信息

Daru. 2013 Jul 18;21(1):59. doi: 10.1186/2008-2231-21-59.

Abstract

BACKGROUND

Pain following surgical removal of impacted molars has remained an important concern among practitioners. Various protocols have been proposed to reduce postoperative pain. However, each one has special side effects and limitations. As green tea possesses anti-inflammatory and antibacterial properties, the aim of the current study was to evaluate the effectiveness of green tea mouthwash in controlling postoperative pain.

MATERIALS AND METHODS

In a study with split-mouth and double blind design, 44 patients in need of bilateral removal of impacted third molars underwent randomized surgical extraction; following one surgery patients rinsed with a green tea mouthwash from the first to seventh postoperative day and after other extraction rinsed with placebo mouthwash in the same duration. Both patients and surgeon were blinded to the type of mouthwash. The predictor variable was type of mouthwash and primary outcome variable was postoperative pain measured by visual analogue scale (VAS) during first week after surgery. In addition, number of analgesics patients used after surgery recorded. To measure the effect of green tea mouthwash, repeated measures test with confidence interval of 95% was performed.

RESULTS

Total of 43 patients with mean age of 24 years underwent total of 86 surgeries. VAS value had no statistically difference prior rinsing among groups (P-value > 0.05). However, the mean value of VAS following rinsing with green tea was statistically lower than placebo in postoperative days of 3-7 (P-value < 0.05). In addition, while rinsing with green tea, patients took significantly lower number of analgesics after surgery (P-value < 0.05). No side effects reported.

CONCLUSION

Green tea mouthwash could be an appropriate and safe choice to control postoperative pain after third molar surgery.

摘要

背景

在外科医生中,拔除阻生磨牙后的疼痛仍然是一个重要关注点。已经提出了各种方案来减轻术后疼痛。然而,每种方案都有特殊的副作用和局限性。由于绿茶具有抗炎和抗菌特性,因此本研究旨在评估绿茶漱口水控制术后疼痛的效果。

材料和方法

在一项采用分侧、双盲设计的研究中,44 名需要双侧拔除阻生第三磨牙的患者接受了随机手术拔除;在一侧手术后,患者在术后第 1 至第 7 天用绿茶漱口水漱口,另一侧手术后在相同时间内用安慰剂漱口水漱口。患者和外科医生都对漱口水的类型不知情。预测变量是漱口水的类型,主要结果变量是术后第 1 周通过视觉模拟量表(VAS)测量的术后疼痛。此外,还记录了患者手术后使用的镇痛药数量。为了衡量绿茶漱口水的效果,进行了具有 95%置信区间的重复测量检验。

结果

共有 43 名年龄平均为 24 岁的患者接受了总共 86 次手术。在漱口前,各组之间 VAS 值无统计学差异(P 值>0.05)。然而,在用绿茶漱口后的第 3-7 天,VAS 的平均值明显低于安慰剂组(P 值<0.05)。此外,在用绿茶漱口时,患者手术后服用的镇痛药数量明显减少(P 值<0.05)。未报告任何副作用。

结论

绿茶漱口水可能是控制第三磨牙手术后术后疼痛的一种合适且安全的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb20/3720195/0e6191a90ebc/2008-2231-21-59-1.jpg

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