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使用α替代器进行透视下操作治疗腹膜导管位置异常的疗效与安全性。

Efficacy and safety of fluoroscopic manipulation using the alpha-replacer for peritoneal catheter malposition.

作者信息

Saka Yosuke, Ito Yasuhiko, Iida Yoshiyasu, Maruyama Shoichi, Matsuo Seiichi

机构信息

Department of Internal Medicine, Kasugai Municipal Hospital, 1-1-1 Takakicho, Kasugai, 486-8510, Aichi, Japan.

Department of Nephrology, Nagoya University Graduate School of Medicine, Showaku, Nagoya, Aichi, Japan.

出版信息

Clin Exp Nephrol. 2015 Jun;19(3):521-6. doi: 10.1007/s10157-014-1007-9. Epub 2014 Jul 17.

Abstract

BACKGROUND

Catheter malposition is one of the reasons for outflow failure in peritoneal dialysis (PD) patients. Fluoroscopic manipulation is a non-surgical treatment option for catheter malposition. We retrospectively analyzed the efficacy and safety of fluoroscopic manipulation using an alpha-replacer guidewire.

METHODS

The alpha-replacer (JMS Co. Ltd., Tokyo, Japan) is a guidewire for the treatment of catheter malposition. We used the alpha-replacer in 23 PD cases at our hospital from January 2008 to December 2012. We evaluated body mass index, time interval between catheter placement and malposition, and interval between catheter exteriorization and malposition. Primary failure was defined as malposition at the time of catheter exteriorization, and secondary failure as malposition after functional PD therapy (correct position at time of exteriorization).

RESULTS

Successful catheter replacement rate using the alpha-replacer was 60.8 % (14 of 23 cases). This was similar to the rates in previous reports. Successful replacement was mostly observed in those with a long interval between catheter placement and malposition (p = 0.048), between catheter placement and exteriorization (p = 0.047) and with secondary failure (p = 0.030). In multivariate analysis, secondary failure cases had a higher rate of successful replacement than primary failure cases (odds ratio [OR] 7.33, p = 0.038). Serious complications, such as abdominal trauma or peritonitis, were not observed.

CONCLUSION

Fluoroscopic manipulation using an alpha-replacer may be safe and effective for the management of peritoneal catheter malposition, particularly in patients who were under functional PD therapy until catheter malposition.

摘要

背景

导管位置不当是腹膜透析(PD)患者引流失败的原因之一。透视下操作是治疗导管位置不当的一种非手术治疗选择。我们回顾性分析了使用α-替换导丝进行透视下操作的疗效和安全性。

方法

α-替换导丝(日本东京JMS有限公司)是一种用于治疗导管位置不当的导丝。2008年1月至2012年12月,我们在我院23例PD患者中使用了α-替换导丝。我们评估了体重指数、导管置入与位置不当之间的时间间隔,以及导管引出与位置不当之间的间隔。原发性失败定义为导管引出时位置不当,继发性失败定义为功能性PD治疗后(引出时位置正确)出现位置不当。

结果

使用α-替换导丝成功更换导管的比例为60.8%(23例中的14例)。这与既往报道的比例相似。成功更换大多见于导管置入与位置不当间隔时间长的患者(p = 0.048)、导管置入与引出间隔时间长的患者(p = 0.047)以及继发性失败的患者(p = 0.030)。多因素分析显示,继发性失败病例成功更换的比例高于原发性失败病例(比值比[OR] 7.33,p = 0.038)。未观察到严重并发症,如腹部创伤或腹膜炎。

结论

使用α-替换导丝进行透视下操作可能对腹膜导管位置不当的处理安全有效,尤其是对于在导管位置不当之前接受功能性PD治疗的患者。

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