Division of Nephrology, McMaster University, Hamilton, Canada.
Clin J Am Soc Nephrol. 2012 May;7(5):795-800. doi: 10.2215/CJN.09850911. Epub 2012 Feb 23.
Mechanical failure of the peritoneal dialysis (PD) catheter is an important cause of technique failure. Fluoroscopic guidewire manipulation may be undertaken in an attempt to correct the failure. The purpose of this study was to determine the efficacy of fluoroscopic manipulation of previously embedded PD catheters, the factors associated with successful manipulation, and the complication rate associated with manipulation.
DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: A single-center, retrospective review of 70 consecutive PD patients undergoing fluoroscopic manipulation for mechanical failure of their PD catheter from June 2006 to February 2011 was undertaken. Logistic regression models were developed to determine the variables associated with successful manipulation.
Of the 70 manipulations, 44 were successful (62.9%). In univariate analysis, catheters located in the pelvis compared with those in the upper abdomen (73.5% versus 42.9%, P=0.01) and catheters that were previously functional compared with those that failed at exteriorization (75.0% versus 46.7%, P=0.04) were more likely to be successfully manipulated. Time embedded, previous hemodialysis, and number of intra-abdominal surgeries were not correlated with likelihood of successful manipulation. In multivariate analysis, catheters located in the pelvis (P=0.01) and those with secondary failure (P=0.01) were more likely to successfully manipulated. Two of the patients developed peritonitis (2.9%), neither requiring cessation of PD.
Fluoroscopic manipulation is an effective and safe therapy for failed PD catheters that are unresponsive to conservative treatment. Properly positioned catheters and those that were previously functional are more likely to be successfully manipulated.
腹膜透析(PD)导管机械故障是技术失败的一个重要原因。可能会进行透视导丝操作,以尝试纠正故障。本研究旨在确定透视操作先前嵌入的 PD 导管的疗效,与成功操作相关的因素以及与操作相关的并发症发生率。
设计、地点、参与者和测量方法:对 2006 年 6 月至 2011 年 2 月期间因 PD 导管机械故障而接受透视操作的 70 例连续 PD 患者进行了单中心回顾性研究。建立逻辑回归模型以确定与成功操作相关的变量。
在 70 次操作中,有 44 次成功(62.9%)。在单变量分析中,与上腹部相比,位于骨盆中的导管(73.5%比 42.9%,P=0.01)和先前功能正常的导管比外露失败的导管(75.0%比 46.7%,P=0.04)更有可能成功操作。嵌入时间,先前的血液透析和腹部手术次数与成功操作的可能性无关。在多变量分析中,位于骨盆中的导管(P=0.01)和继发性失败的导管(P=0.01)更有可能成功操作。两名患者发生腹膜炎(2.9%),均无需停止 PD。
透视操作是一种有效且安全的治疗方法,适用于对保守治疗无反应的失败 PD 导管。位置适当的导管和以前功能正常的导管更有可能成功操作。