Finis D, Pischel N, König C, Hayajneh J, Borrelli M, Schrader S, Geerling G
Augenklinik, Heinrich-Heine-Universität Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Deutschland,
Ophthalmologe. 2014 Nov;111(11):1050-6. doi: 10.1007/s00347-014-3042-z.
For the diagnosis of dry eye, taking an accurate medical history of the patient is critical. For this purpose the ocular surface disease index (OSDI) can be regarded as the established standard questionnaire but the standard patient evaluation of eye dryness (SPEED) questionnaire has recently been developed. The advantages of the SPEED questionnaire are the lower number of questions and easier interpretability.
In a retrospective analysis of 153 patients of our special clinic for dry eyes we performed a comparison of the SPEED with the established OSDI questionnaire regarding the evaluation of the severity of dry eye. In addition, we analyzed possible correlations with various objective parameters for classification of dry eye syndrome.
There was a highly significant correlation between OSDI and SPEED values with a correlation coefficient of 0.47 (p < 0.001). In addition, significant correlations between OSDI values and the tear meniscus height (r = - 0.1374, p = 0.0226), Schirmer values (r = - 0.26, p < 0.0001) and lid margins parallel conjunctival folds (r = 0.1261, p = 0.034) were observed. The SPEED values showed a significant correlation with age (r = - 0.2106, p = 0.0107) and lipid layer thickness (r = - 0.159, p = 0.0081).
The OSDI and SPEED questionnaires are both suitable for detecting the symptoms of dry eye; however the results of the questionnaires cannot be used interchangeably. While the SPEED levels seemed to correlate more with the parameters of evaporative dry eye, the OSDI values were more correlated with parameters of aqueous tear-deficient dry eye. However, a distinction between evaporative and aqueous tear-deficient dry eye is not possible based only on the results of the questionnaires.
对于干眼症的诊断,准确了解患者的病史至关重要。为此,眼表疾病指数(OSDI)可被视为既定的标准问卷,但标准干眼患者评估(SPEED)问卷最近已被开发出来。SPEED问卷的优点是问题数量较少且更易于解读。
在对我们干眼症专科门诊的153例患者进行的回顾性分析中,我们就干眼症严重程度的评估,对SPEED问卷与既定的OSDI问卷进行了比较。此外,我们分析了与干眼综合征分类的各种客观参数之间可能存在的相关性。
OSDI值与SPEED值之间存在高度显著的相关性,相关系数为0.47(p < 0.001)。此外,观察到OSDI值与泪河高度(r = -0.1374,p = 0.0226)、泪液分泌试验值(r = -0.26,p < 0.0001)以及睑缘平行结膜皱襞(r = 0.1261,p = 0.034)之间存在显著相关性。SPEED值与年龄(r = -0.2106,p = 0.0107)和脂质层厚度(r = -0.159,p = 0.0081)显示出显著相关性。
OSDI问卷和SPEED问卷都适用于检测干眼症的症状;然而,问卷结果不能相互替代使用。虽然SPEED水平似乎与蒸发型干眼症的参数相关性更强,但OSDI值与水样液缺乏性干眼症的参数相关性更强。然而,仅根据问卷结果无法区分蒸发型和水样液缺乏型干眼症。