Valenti W M, Jenzer M, Bentley D W
Am Rev Respir Dis. 1978 Feb;117(2):233-8. doi: 10.1164/arrd.1978.117.2.233.
Type-specific pneumococcal respiratory disease was studied in a chronic-disease hospital during a 27-month period. Isolates from 50 patients with pneumonia and from 24 patients with chronic bronchitis were available for typing. Vaccine types were isolated from 74 per cent of patients with pneumonia and from 42 per cent of patients with chronic bronchitis. Pneumococcal types isolated from 5 of 8 patients with bacteremia and from 6 of 9 patients who died were also included in the vaccine. The data suggest that, theoretically, closed populations of elderly and chronically ill patients would benefit from vaccination in an attempt to control pneumococcal pneumonia. Less clear is the potential role vaccination in patients with chronic bronchitis.
在一家慢性病医院对特定类型的肺炎球菌呼吸道疾病进行了为期27个月的研究。从50例肺炎患者和24例慢性支气管炎患者中分离出的菌株可供分型。74%的肺炎患者和42%的慢性支气管炎患者分离出疫苗型菌株。从8例菌血症患者中的5例以及9例死亡患者中的6例分离出的肺炎球菌类型也包含在疫苗中。数据表明，从理论上讲，老年和慢性病患者的封闭人群通过接种疫苗来控制肺炎球菌肺炎可能会受益。而疫苗接种在慢性支气管炎患者中的潜在作用尚不清楚。
