Fattahi Masoum Seyd Hossein, Feizzdeh Kerigh Behzad, Goreifi Alireza
Transplant Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran.
Minimally Invasive Surgery Research Center, Kidney Transplantation Complications Research Center, Ghaem Medical Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran.
Nephrourol Mon. 2014 May 3;6(3):e17258. doi: 10.5812/numonthly.17258. eCollection 2014 May.
Pulmonary metastases are often found in advanced malignancies. Urogenital malignancies originating from kidney, prostate, testes, and bladder all metastasize preferentially to the lungs.
This retrospective study aimed to evaluate the results of pulmonary and chest wall metastasectomy in patients with primary urogenital Tumors.
The patients who underwent pulmonary metastasectomy in Ghaem Hospital from 1996 to 2011 were examined. Thirteen out of 79 patients referred for pulmonary metastasectomy to a single thoracic surgeon had metastases from urogenital tumors; two cases with metastasis from urogenital tumors were inoperable. We reviewed their demographic data and also clinicopathological features. Disease free interval (DFI) was defined as the time between the first curative surgery and the appearance of the signs and symptoms of pulmonary metastasis.
Among 11 patients who underwent surgery consisted of eight males and three females. Their metastasis originated from testis tumors (n = 5), renal cell carcinoma (RCC; n = 4), bladder tumor (n = 1), and prostate cancer (n = 1). Their mean age was 41.27 years (range, 21-67). The mean age of the patients with RCC and testis tumor at the time of diagnosing metastasis was 54 and 24.8 years, respectively. There were two other patients (a 62-year-old female and a 54-year-old male) with pleural effusion due to metastatic RCC whose tumor was inoperable because of their poor general condition and hence, were referred for chemotherapy.
Pulmonary metastasectomy is feasible in selected cases.
肺转移瘤常见于晚期恶性肿瘤。起源于肾脏、前列腺、睾丸和膀胱的泌尿生殖系统恶性肿瘤均优先转移至肺部。
本回顾性研究旨在评估原发性泌尿生殖系统肿瘤患者行肺及胸壁转移瘤切除术的效果。
对1996年至2011年在加姆医院接受肺转移瘤切除术的患者进行检查。79例因肺转移瘤转诊至一名胸外科医生处的患者中，13例有泌尿生殖系统肿瘤转移；2例泌尿生殖系统肿瘤转移患者无法手术。我们回顾了他们的人口统计学数据以及临床病理特征。无病间期（DFI）定义为首次根治性手术与肺转移体征和症状出现之间的时间。
11例接受手术的患者中，男性8例，女性3例。他们的转移瘤分别起源于睾丸肿瘤（n = 5）、肾细胞癌（RCC；n = 4）、膀胱肿瘤（n = 1）和前列腺癌（n = 1）。他们的平均年龄为41.27岁（范围21 - 67岁）。诊断转移时，RCC和睾丸肿瘤患者的平均年龄分别为54岁和24.8岁。另外两名患者（一名62岁女性和一名54岁男性）因转移性RCC出现胸腔积液，由于全身状况差，其肿瘤无法手术，因此转诊接受化疗。
在某些特定病例中，肺转移瘤切除术是可行的。
