患者自述的过敏史是全髋关节和膝关节置换术预后不良的一个风险因素。
Patient reported allergies are a risk factor for poor outcomes in total hip and knee arthroplasty.
作者信息
Graves Christopher M, Otero Jesse E, Gao Yubo, Goetz Devon D, Willenborg Melissa D, Callaghan John J
机构信息
Department of Orthopaedics and Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, Iowa.
Des Moines Orthopaedic Surgeons, West Des Moines, Iowa.
出版信息
J Arthroplasty. 2014 Sep;29(9 Suppl):147-9. doi: 10.1016/j.arth.2014.02.040. Epub 2014 Jun 6.
We evaluated 459 patients undergoing THA or TKA who completed preoperative and postoperative WOMAC and/or SF36 surveys. Medical comorbidities and reported allergies were also recorded. Evaluation of surveys was compared for patients with or without 4 or more reported allergies using statistical methods. Patients with 4 or more reported allergies had less improvement on SF36 Physical Component Score (∆PCS=4.2) than those with 0-3 allergies (∆PCS=10.0, P=0.0002). Regression analysis showed that this change was independent of self-reported comorbidities. Patients reporting 4 or more allergies also had less improvement in WOMAC function (∆F=21.4) than those with 0-3 allergies (∆F = 27.2, P=0.036). Similar nonsignificant trends occurred in SF36 mental and WOMAC pain and stiffness scores.
我们评估了459例行全髋关节置换术（THA）或全膝关节置换术（TKA）的患者，这些患者均完成了术前和术后的Western Ontario and McMaster Universities骨关节炎指数（WOMAC）和/或36项简明健康状况调查（SF36）。同时记录了患者的内科合并症及所报告的过敏情况。采用统计学方法比较了报告有4种或更多过敏情况的患者与无此情况患者的调查评估结果。报告有4种或更多过敏情况的患者在SF36身体成分评分（∆PCS = 4.2）方面的改善程度低于有0 - 3种过敏情况的患者（∆PCS = 10.0，P = 0.0002）。回归分析表明，这种变化与自我报告的合并症无关。报告有4种或更多过敏情况的患者在WOMAC功能方面的改善程度（∆F = 21.4）也低于有0 - 3种过敏情况的患者（∆F = 27.2，P = 0.036）。在SF36心理评分以及WOMAC疼痛和僵硬评分方面也出现了类似的非显著趋势。
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