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外科医生的期望能否预测全髋关节置换术(THA)和全膝关节置换术(TKA)后WOMAC评分在临床上的显著改善?

Do Surgeon Expectations Predict Clinically Important Improvements in WOMAC Scores After THA and TKA?

作者信息

Ghomrawi Hassan M K, Mancuso Carol A, Dunning Allison, Gonzalez Della Valle Alejandro, Alexiades Michael, Cornell Charles, Sculco Thomas, Bostrom Matthias, Mayman David, Marx Robert G, Westrich Geoffrey, O'Dell Michael, Mushlin Alvin I

机构信息

Department of Surgery, Feinberg School of Medicine, Northwestern University, 20th Floor, 633 N Saint Claire, Chicago, IL, 60611, USA.

Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.

出版信息

Clin Orthop Relat Res. 2017 Sep;475(9):2150-2158. doi: 10.1007/s11999-017-5331-8. Epub 2017 Mar 28.

Abstract

BACKGROUND

Failure of THA or TKA to meet a patient's expectations may result in patient disappointment and litigation. However, there is little evidence to suggest that surgeons can consistently anticipate which patients will benefit from those interventions.

QUESTIONS/PURPOSES: To determine the ability of surgeons to identify, in advance of surgery, patients who will benefit from THA or TKA and those who will not, where 'benefit' is defined as a clinically important improvement in a validated patient-reported outcomes score.

METHODS

In this prospective study, eight high-volume orthopaedic surgeons completed validated THA and TKA expectations questionnaires (score 0-100, 100 being the highest expectation) as part of preoperative assessment of all their patients scheduled for a THA or TKA and enrolled in the Hospital for Special Surgery institutional registry. Enrolled patients completed the WOMAC preoperatively and at 2 years. Successful outcomes were defined as achieving the minimum clinically important difference (MCID) in WOMAC pain and function subscales. Sensitivity, specificity, and receiver operating characteristic (ROC) curves were used to evaluate the ability of surgeons' expectation scores to identify patients likely to achieve the MCID on the WOMAC scale. Analyses were run separately for patients having THA and TKA. We enrolled 259 patients undergoing THA and 247 undergoing TKA, of whom 77% (n = 200) and 77% (n = 191) completed followup surveys 2 years after their procedures, respectively.

RESULTS

Surgeons' expectation scores effectively anticipated patients who would improve after THA, but they were no better than chance in identifying patients who would achieve the MCID on the WOMAC score 2 years after TKA. For patients having THA, the areas under the ROC curve were 0.67 (95% CI, 0.53-0.82; p = 0.02) and 0.74 (95% CI, 0.63-0.85; p < 0.01) for WOMAC function and pain outcomes, respectively, indicating good accuracy. Sensitivity and specificity were maximized on WOMAC pain and function scores (sensitivity = 0.69, specificity = 0.72, both for pain and function) at an expectations score of 83 or greater of 100. Surgeons' expectations were more accurate for patients who were men, who had a BMI less than 30 kg/m, who had more than one comorbidity, and who were older than 65 years. For patients having TKA, surgeons' expectation scores were not better than chance for identifying those who would experience a clinically important improvement on the WOMAC scale (area under ROC curve: Function = 0.51, [95% CI, 0.42-0.61], p = 0.78; Pain = 0.51, [95% CI, 0.40-0.61], p = 0.92).

CONCLUSIONS

Most patients having THA and TKA achieved the MCID improvement after surgery. However, the inability of surgeons' expectation scores to discriminate accurately between patients who benefit and those who do not among patients scheduled for THA who are young, with no comorbidities, and with elevated BMIs, and among all patients scheduled for TKA, calls for surgeons to spend more time with these patients to fully understand and address their needs and expectations. Using standardized assessment tools to compare surgeons' expectations and those of their patients may help focus the surgeon-patient discussion further, and address patients' expectations more effectively.

LEVEL OF EVIDENCE

Level II, therapeutic study.

摘要

背景

全髋关节置换术(THA)或全膝关节置换术(TKA)未能达到患者的期望可能会导致患者失望并引发诉讼。然而,几乎没有证据表明外科医生能够始终如一地预测哪些患者将从这些干预措施中受益。

问题/目的:确定外科医生在手术前识别哪些患者将从THA或TKA中受益以及哪些患者不会受益的能力,其中“受益”定义为在经过验证的患者报告结局评分中出现具有临床意义的改善。

方法

在这项前瞻性研究中,八位高年资骨科医生完成了经过验证的THA和TKA期望问卷(评分0 - 100,100分为最高期望),作为其所有计划进行THA或TKA并纳入特种外科医院机构登记处的患者术前评估的一部分。纳入的患者在术前和术后2年完成了WOMAC问卷。成功的结局定义为在WOMAC疼痛和功能子量表中达到最小临床重要差异(MCID)。敏感性、特异性和受试者工作特征(ROC)曲线用于评估外科医生的期望评分识别可能在WOMAC量表上达到MCID的患者的能力。对接受THA和TKA的患者分别进行分析。我们纳入了259例接受THA的患者和247例接受TKA的患者,其中分别有77%(n = 200)和77%(n = 191)在术后2年完成了随访调查。

结果

外科医生的期望评分有效地预测了THA术后会改善的患者,但在识别TKA术后2年在WOMAC评分中达到MCID的患者方面,并不比随机猜测更好。对于接受THA的患者,WOMAC功能和疼痛结局的ROC曲线下面积分别为0.67(95% CI,0.53 - 0.82;p = 0.02)和0.74(95% CI,0.63 - 0.85;p < 0.01),表明准确性良好。当期望评分为100分中的83分或更高时,WOMAC疼痛和功能评分的敏感性和特异性达到最大值(疼痛和功能的敏感性均为0.69,特异性均为0.72)。外科医生的期望对于男性患者、BMI小于30 kg/m²的患者、患有多种合并症的患者以及年龄大于65岁的患者更准确。对于接受TKA的患者,外科医生的期望评分在识别那些在WOMAC量表上会有临床重要改善的患者方面并不比随机猜测更好(ROC曲线下面积:功能 = 0.51,[95% CI,0.42 - 0.61],p = 0.78;疼痛 = 0.51,[95% CI,0.40 - 0.61],p = 0.92)。

结论

大多数接受THA和TKA的患者术后实现了MCID改善。然而,外科医生的期望评分无法在计划接受THA的年轻、无合并症且BMI升高的患者以及所有计划接受TKA的患者中准确区分受益患者和非受益患者,这就要求外科医生花更多时间与这些患者交流,以充分理解并满足他们的需求和期望。使用标准化评估工具来比较外科医生和患者的期望可能有助于进一步聚焦医患讨论,并更有效地满足患者的期望。

证据水平

II级,治疗性研究。

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