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缓解期双相情感障碍中的冲动性是一种稳定的特质吗?一项元分析综述。

Is impulsivity in remitted bipolar disorder a stable trait? A meta-analytic review.

作者信息

Saddichha Sahoo, Schuetz Christian

机构信息

North Western Mental Health, Melbourne Health, Melbourne, VIC, Australia.

Department of Psychiatry, University of British Columbia, Vancouver, Canada.

出版信息

Compr Psychiatry. 2014 Oct;55(7):1479-84. doi: 10.1016/j.comppsych.2014.05.010. Epub 2014 May 24.

DOI:10.1016/j.comppsych.2014.05.010
PMID:25035161
Abstract

OBJECTIVE

To review scores on measures of impulsivity in remitted bipolar disorder.

DATA SOURCE

We used keywords "impulsivity and bipolar" and "impulsivity and mania" to narrow down our search on Medline, EMBASE and Psychinfo to include those studies that had reported impulsivity scores using validated and reliable assessment measures in remitted bipolar disorder (both I and II). We searched all English language studies from 1990 to October 2012.

STUDY SELECTION

Nineteen reports met the inclusion criteria and were reviewed by two abstractors independently.

DATA ABSTRACTION

We generated weighted mean differences (WMDs) from pooled data using RevManager 5.0 from Cochrane analysis.

RESULTS

The Barratt Impulsivity Scale (BIS) 11 was the instrument most commonly used. Nineteen studies met the inclusion criteria, of which 2 were excluded due to incomplete data. A WMD of 12.8 was observed for BIS 11 total scores, 4.3 on the motor component, 4.1 on the cognitive and 7.6 on the non-planning components of the BIS 11 respectively.

CONCLUSION

Impulsivity is significantly higher in remitted bipolar patients than normal controls. Non-planning impulsivity is a key domain affected in bipolar disorder, which may represent a stable trait.

摘要

目的

回顾缓解期双相情感障碍患者冲动性测量指标的得分情况。

数据来源

我们使用关键词“冲动性与双相情感障碍”以及“冲动性与躁狂”在医学文献数据库(Medline)、荷兰医学文摘数据库(EMBASE)和心理学文摘数据库(Psychinfo)中进行检索,以筛选出那些使用经过验证且可靠的评估方法报告缓解期双相情感障碍(I型和II型)患者冲动性得分的研究。我们检索了1990年至2012年10月期间所有的英文研究。

研究选择

19篇报告符合纳入标准,由两名摘要提取人员独立进行审查。

数据提取

我们使用Cochrane分析的RevManagerv5.0软件从汇总数据中生成加权平均差(WMD)。

结果

巴雷特冲动性量表(BIS)-11是最常用的工具。19项研究符合纳入标准,其中2项因数据不完整被排除。BIS-11总分的加权平均差为12.8,运动分量表得分的加权平均差为4.3,认知分量表得分为4.1,非计划性分量表得分为7.6。

结论

缓解期双相情感障碍患者的冲动性显著高于正常对照组。非计划性冲动是双相情感障碍中受影响的一个关键领域,可能代表一种稳定的特质。

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