Sa'do B, Tashiro H
1st Department of Oral Surgery, Faculty of Dentistry, Kyushu University, Fukuoka, Japan.
Int J Oral Maxillofac Surg. 1989 Jun;18(3):175-8. doi: 10.1016/s0901-5027(89)80121-3.
The effect of periosteal elevation on the growth of the mandible was investigated in 142 3-week-old male rats. Surgery was performed at 3 weeks of age, and the animals were sacrificed at 6, 9, and 15 weeks of age. Measurements were carried out on dried halves of the mandibles. A bone defect was found at the 3rd week postoperatively but had filled in at the 6th week postoperatively. Histological and microangiographical studies were carried out up to the 6th week postoperatively. No significant differences were recorded in the size of the operated and unoperated halves of the mandibles. The growth pattern for the experimental group tended to be similar to that of the control group. It is therefore concluded that periosteal elevation alone does not induce growth impairment in the mandible of young rats.
在142只3周龄雄性大鼠中研究了骨膜掀起对下颌骨生长的影响。手术在3周龄时进行，动物分别在6周龄、9周龄和15周龄时处死。对下颌骨的干燥半块进行测量。术后第3周发现骨缺损，但术后第6周已填充。术后直至第6周进行了组织学和微血管造影研究。手术侧和未手术侧下颌骨的大小未记录到显著差异。实验组的生长模式倾向于与对照组相似。因此得出结论，单纯骨膜掀起不会导致幼鼠下颌骨生长受损。
