Acil Hande, Cavdar Ikbal
Surgical Nursing Department, School of Health, Sakarya University, Sakarya, Turkey E-mail :
Asian Pac J Cancer Prev. 2014;15(13):5377-81. doi: 10.7314/apjcp.2014.15.13.5377.
The aim of this study was to investigate the differences in quality of life in patients who received breast conserving surgery (BCS) or modified radical mastectomy (MRM) for breast cancer.
A total of 100 women with breast cancer who underwent either BCS or MRM between September 2011 and April 2012 at a private health center and completed their chemotherapy and radiation therapy cycles were included in the study. To assess the quality of life, we used a demographic questionnaire, the European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) and the Quality of Life assessment in Breast Cancer (EORTC QLQ-BR23).
Using QLQ-C30, we found that patients who underwent BCS had better functional status and fewer symptoms than patients who underwent MRM. In QLQ-BR23, independent factors improving the functional scales were BCS, higher level of education and marital status (married); independent factors improving symptoms were BCS, higher level of education, younger age and low and normal body mass index (BMI). In QLQ-C30, independent factors affecting the functional and symptom scales were only BCS and higher level of education.
We determined that patients who received BCS had better functional status and less frequent symptoms than patients who underwent MRM.
本研究旨在调查接受保乳手术(BCS)或改良根治性乳房切除术(MRM)治疗乳腺癌的患者在生活质量方面的差异。
本研究纳入了2011年9月至2012年4月期间在一家私立健康中心接受BCS或MRM手术并完成化疗和放疗周期的100名乳腺癌女性患者。为评估生活质量,我们使用了一份人口统计学调查问卷、欧洲癌症研究与治疗组织生活质量问卷(EORTC QLQ-C30)以及乳腺癌生活质量评估问卷(EORTC QLQ-BR23)。
使用QLQ-C30,我们发现接受BCS的患者比接受MRM的患者具有更好的功能状态和更少的症状。在QLQ-BR23中,改善功能量表的独立因素为BCS、较高的教育水平和婚姻状况(已婚);改善症状的独立因素为BCS、较高的教育水平、较年轻的年龄以及低和正常的体重指数(BMI)。在QLQ-C30中,影响功能和症状量表的独立因素仅为BCS和较高的教育水平。
我们确定接受BCS的患者比接受MRM的患者具有更好的功能状态和更不频繁的症状。