一例口腔浆母细胞淋巴瘤及与人类免疫缺陷病毒感染相关口腔表现的当前趋势综述。

A case of oral plasmablastic lymphoma and review of current trends in oral manifestations associated with human immunodeficiency virus infection.

作者信息

Medel Nicholas, Hamao-Sakamoto Aya

机构信息

Resident, Parkland Memorial Hospital, Oral and Maxillofacial Surgery Division, Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX.

Assistant Professor, Oral and Maxillofacial Surgery Division, Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX.

出版信息

J Oral Maxillofac Surg. 2014 Sep;72(9):1729-35. doi: 10.1016/j.joms.2014.04.009. Epub 2014 Apr 21.

DOI:10.1016/j.joms.2014.04.009

PMID:25043145

Abstract

Plasmablastic lymphoma (PBL) is a rare and aggressive type of non-Hodgkin lymphoma that in 2000 was classified as a distinct type of lymphoma related to acquired immune deficiency syndrome by the World Health Organization after the first reports of the disease surfaced in 1997. PBL is strongly associated with human immunodeficiency virus (HIV) infection and often occurs within the oral cavity. Despite intensive chemotherapy regimens and combinational antiretroviral therapy, the prognosis of PBL in HIV-infected patients remains poor. This article describes a case of oral PBL and a literature review of current trends in oral manifestations associated with HIV infection.

摘要

浆母细胞淋巴瘤（PBL）是一种罕见且侵袭性强的非霍奇金淋巴瘤，1997年该病首次报道后，2000年世界卫生组织将其归类为与获得性免疫缺陷综合征相关的一种独特类型的淋巴瘤。PBL与人类免疫缺陷病毒（HIV）感染密切相关，且常发生于口腔内。尽管有强化化疗方案和联合抗逆转录病毒疗法，但HIV感染患者中PBL的预后仍然很差。本文描述了一例口腔PBL病例，并对与HIV感染相关的口腔表现的当前趋势进行了文献综述。