Vale Daniela Assis do, Rogado Carolina Martelli, Carvalho Danielle Lima Corrêa de, Trierveiler Marilia, Ortega Karem López
Post-graduation Program in Dental Sciences -Area of Oral and Maxillofacial Pathology and Special Patients of the Faculdade de Odontologia - Universidade de São Paulo (FO-USP) - São Paulo (SP), Brazil.
Special Care Dentistry Center, Faculdade de Odontologia - Universidade de São Paulo (CAPE-FOUSP), São Paulo (SP), Brazil.
An Bras Dermatol. 2017;92(5 Suppl 1):110-112. doi: 10.1590/abd1806-4841.20175417.
Plasmablastic lymphoma is a non-Hodgkin lymphoma characterized by its plasmacytic differentiation and predilection for the oral cavity. It is among the lymphomas most commonly associated with AIDS. This report details a case of a HIV-positive patient with a 1-month history of an exophytic mass in the gingival area of the upper left quadrant. The diagnosis of plasmablastic lymphoma was made based on its histopathological and immunophenotypical features. She was treated with chemotherapy followed by autologous hematopoietic stem cell transplantation. Despite complete resolution of the lesion, the patient died of cardiorespiratory arrest. This case illustrates plasmablastic lymphoma as the first clinical manifestation of AIDS, highlighting the importance of differentiating between a potentially malignant lesion and other pathologic processes.
浆母细胞性淋巴瘤是一种非霍奇金淋巴瘤，其特征为浆细胞分化且好发于口腔。它是最常与艾滋病相关的淋巴瘤之一。本报告详细介绍了一例HIV阳性患者，该患者左上象限牙龈区域有一个外生性肿物，病史1个月。根据组织病理学和免疫表型特征诊断为浆母细胞性淋巴瘤。她接受了化疗，随后进行了自体造血干细胞移植。尽管病变完全消退，但患者死于心肺骤停。该病例表明浆母细胞性淋巴瘤可作为艾滋病的首发临床表现，凸显了区分潜在恶性病变与其他病理过程的重要性。
