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Int J Hyg Environ Health. 2013 Jul;216(4):445-60. doi: 10.1016/j.ijheh.2012.12.003. Epub 2013 Feb 17.
2
Smoking and suicidal behaviours in a sample of US adults with low mood: a retrospective analysis of longitudinal data.美国情绪低落成年人样本中的吸烟与自杀行为:纵向数据的回顾性分析
BMJ Open. 2012 Jun 8;2(3). doi: 10.1136/bmjopen-2012-000876. Print 2012.
3
Worldwide impact of economic cycles on suicide trends over 3 decades: differences according to level of development. A mixed effect model study.经济周期对三十年自杀趋势的全球影响:根据发展水平的差异。一项混合效应模型研究。
BMJ Open. 2012 May 14;2(3). doi: 10.1136/bmjopen-2011-000785. Print 2012.
4
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Neurotoxicology. 2011 Dec;32(6):718-24. doi: 10.1016/j.neuro.2011.08.002. Epub 2011 Aug 19.
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First reported outbreak of green tobacco sickness in Brazil.巴西首次报告暴发绿烟病疫情。
Cad Saude Publica. 2010 Dec;26(12):2263-9. doi: 10.1590/s0102-311x2010001200005.
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Mood disorders hospitalizations, suicide attempts, and suicide mortality among agricultural workers and residents in an area with intensive use of pesticides in Brazil.巴西一个高度使用农药的地区的农业工人和居民中的情绪障碍住院、自杀未遂和自杀死亡率。
J Toxicol Environ Health A. 2010;73(13-14):866-77. doi: 10.1080/15287391003744781.
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Serum cholinesterase inhibition in relation to paraoxonase-1 (PON1) status among organophosphate-exposed agricultural pesticide handlers.有机磷暴露的农业农药处理人员中血清胆碱酯酶抑制与对氧磷酶-1(PON1)状态的关系。
Environ Health Perspect. 2009 Sep;117(9):1402-8. doi: 10.1289/ehp.0900682. Epub 2009 Jun 9.
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Exposure to methamidophos at adulthood elicits depressive-like behavior in mice.成年期接触甲胺磷会引发小鼠的抑郁样行为。
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Tobacco smoking and depression--results from the WHO/ISBRA study.吸烟与抑郁症——世界卫生组织/国际吸烟与健康研究协会的研究结果
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巴西一个烟草种植和农药使用密集地区农业工人的自杀死亡率。

Suicide mortality among agricultural workers in a region with intensive tobacco farming and use of pesticides in Brazil.

机构信息

From the Department of Preventative Medicine (Ms Krawczyk and Ms Fonseca), Icahn School of Medicine at Mount Sinai, New York, NY; Institute for Studies in Collective Health (Dr Meyer), Universidade Federal do Rio de Janeiro; and Department of Biochemistry (Dr Lima), Universidade Federal do Estado do Rio de Janeiro, RJ, Brazil.

出版信息

J Occup Environ Med. 2014 Sep;56(9):993-1000. doi: 10.1097/JOM.0000000000000214.

DOI:10.1097/JOM.0000000000000214
PMID:25046321
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5240450/
Abstract

OBJECTIVE

To investigate whether suicide risk among agricultural workers is higher in regions with heavier pesticide use and/or presence of tobacco farming.

METHODS

Suicide mortality data were gathered from residents of the Brazilian state of Alagoas. Agricultural census data were used to arrange and classify Alagoas cities into distribution groups on the basis of variables concerning pesticide use and/or tobacco farming. Mortality odds ratio calculations were then used to compare suicide risk among agricultural and nonagricultural workers in different groups.

RESULTS

Suicide risk was higher among agricultural workers than among nonagricultural workers, elevated in regions that used more pesticides, and greatest in regions that produced more tobacco.

CONCLUSIONS

This is one of the first studies of its kind to suggest that combined effects of pesticide and tobacco exposure may be linked to higher suicide risk among agricultural workers.

摘要

目的

探究在农药使用量较大和/或存在烟草种植的地区,农业工人的自杀风险是否更高。

方法

从巴西阿拉戈斯州的居民中收集自杀死亡率数据。利用农业普查数据,根据农药使用和/或烟草种植的相关变量,对阿拉戈斯州的城市进行排列和分类,将其分为不同的分布组。然后使用死亡率比值比计算来比较不同组中农业和非农业工人的自杀风险。

结果

与非农业工人相比,农业工人的自杀风险更高,在使用更多农药的地区风险升高,在生产更多烟草的地区风险最高。

结论

这是此类研究中的首例,表明农药和烟草暴露的综合效应可能与农业工人的更高自杀风险有关。