Mahoney Sara E, Loprinzi Paul D
Bellarmine University, Department of Exercise Science, Donna & Allan Lansing School of Nursing & Health Sciences, Louisville, KY.
Bellarmine University, Department of Exercise Science, Donna & Allan Lansing School of Nursing & Health Sciences, Louisville, KY.
J Diabetes Complications. 2014 Nov-Dec;28(6):767-71. doi: 10.1016/j.jdiacomp.2014.06.011. Epub 2014 Jun 21.
(1) Determine the relationship between dietary flavonoid-rich fruit and vegetable consumption on diabetes-related biomarkers (e.g., HgbA1c) and diabetic retinopathy.
Data from 381 participants with diabetes from the NHANES 2003-2006 were analyzed. Blood samples were taken to measure C-reactive protein (CRP), HgbA1C, and fasting glucose and insulin. Diabetic retinopathy was assessed from a retinal imaging exam. A high-flavonoid fruit and vegetable consumption (HFVC) index variable was created from a food frequency questionnaire (FFQ).
After adjustments, greater HFVC was associated (p<0.05) with lower levels of CRP (β=-0.005), HgbA1C (β=-0.005) and glucose (β=-0.59), with greater HFVC reducing the odds of having diabetic retinopathy by 30%.
Adults with diabetes consuming more flavonoid-rich fruits and vegetables had lower degrees of inflammation, better glycemic control, and reduced odds of diabetic retinopathy.
（1）确定富含黄酮类化合物的水果和蔬菜摄入量与糖尿病相关生物标志物（如糖化血红蛋白）及糖尿病视网膜病变之间的关系。
分析了2003 - 2006年美国国家健康与营养检查调查（NHANES）中381名糖尿病患者的数据。采集血样以测量C反应蛋白（CRP）、糖化血红蛋白（HgbA1C）、空腹血糖和胰岛素。通过视网膜成像检查评估糖尿病视网膜病变。根据食物频率问卷（FFQ）创建了一个高黄酮类水果和蔬菜摄入量（HFVC）指数变量。
调整后，较高的HFVC与较低水平的CRP（β = -0.005）、HgbA1C（β = -0.005）和血糖（β = -0.59）相关（p < 0.05），较高的HFVC使患糖尿病视网膜病变的几率降低30%。
摄入更多富含黄酮类化合物的水果和蔬菜的糖尿病成年人炎症程度较低，血糖控制更好，患糖尿病视网膜病变的几率降低。
