Bosch Peggy, Van Luijtelaar Gilles, Van Den Noort Maurits, Schenkwald Julia, Kueppenbender Nicole, Lim Sabina, Egger Jos, Coenen Anton
Donders Institute for Brain, Cognition and Behaviour, Centre for Cognition, Radboud University Nijmegen, Nijmegen, the Netherlands; LVR-Klinik Bedburg-Hau, Kleve, Germany; Division of Acupuncture & Meridian, WHO Collaborating Center for Traditional Medicine, East-West Medical Research Institute and School of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.
Scand J Psychol. 2014 Oct;55(5):513-9. doi: 10.1111/sjop.12152. Epub 2014 Jul 24.
While previous studies on the MMPI-2 in patients with schizophrenia and depression have used mixed samples of both early stage and chronic psychiatric patients. Here, it is investigated whether chronicity itself might have a differential effect on the MMPI-2 profiles of these patients and whether demoralization 'associated with long-term illness' affects the scales of the MMPI-2. Thirty long-term patients with schizophrenia, 30 long-term patients with depression, and 30 healthy participants completed the MMPI-2. Groups were compared on Clinical Scales and on the Restructured Clinical (RC) Scales. Patients with schizophrenia differed from patients with depression on 14 MMPI-2 scales and from healthy controls on 10 scales, generally showing mean UT-scores < 65, indicating a subjective experience of (near) normal functioning. Patients with depression differed from healthy controls on 17 scales mostly with UT-scores > 65, indicating impaired functioning. Demoralization was higher in patients with depression than in patients with schizophrenia and both psychiatric groups differed from the healthy control group. It is concluded that long-term patients with depression show impaired functioning and high demoralization, while long-term patients with schizophrenia surprisingly show near normal functioning and less demoralization.
虽然先前关于精神分裂症和抑郁症患者的明尼苏达多相人格调查表第二版（MMPI - 2）的研究使用了早期和慢性精神病患者的混合样本。在此，研究慢性病本身是否可能对这些患者的MMPI - 2剖面图有不同影响，以及“与长期疾病相关的”士气低落是否会影响MMPI - 2的量表。30名长期精神分裂症患者、30名长期抑郁症患者和30名健康参与者完成了MMPI - 2测试。对各组在临床量表和重组临床（RC）量表上进行了比较。精神分裂症患者在14个MMPI - 2量表上与抑郁症患者不同，在10个量表上与健康对照不同，总体上平均标准分（UT）<65，表明主观体验为（接近）正常功能。抑郁症患者在17个量表上与健康对照不同，大多UT分数>65，表明功能受损。抑郁症患者的士气低落程度高于精神分裂症患者，两个精神病组均与健康对照组不同。研究得出结论，长期抑郁症患者功能受损且士气低落程度高，而长期精神分裂症患者令人惊讶地表现出接近正常的功能且士气低落程度较低。
