电抽搐疗法对精神药物引起的迟发性运动障碍或运动障碍的影响：一项回顾性研究。
The effects of electroconvulsive therapy on tardive dystonia or dyskinesia induced by psychotropic medication: a retrospective study.
机构信息
Department of Neuropsychiatry, Hirosaki University School of Medicine, Hirosaki, Japan.
Department of Neuropsychiatry, Hirosaki University School of Medicine, Hirosaki, Japan ; Department of Neuropsychiatry, Hirosaki-Aiseikai Hospital, Hirosaki, Japan.
出版信息
Neuropsychiatr Dis Treat. 2014 Jul 3;10:1209-12. doi: 10.2147/NDT.S62490. eCollection 2014.
BACKGROUND
Tardive dystonia and dyskinesia are potentially irreversible neurological syndromes. Successful electroconvulsive treatment (ECT) has been reported by multiple sources; however, the existing retrospective reviews and open prospective trials provide little information on the response rate.
METHODS
Eighteen consecutive patients with tardive dystonia or dyskinesia received a standard course of ECT to treat abnormal movement. The severity of the tardive dystonia and dyskinesia was evaluated using the Abnormal Involuntary Movement Scale (AIMS) before and after the course of ECT. The patients who displayed a greater than 50% improvement in the AIMS score were classified as the responders.
RESULTS
The mean AIMS score decreased from 19.1±4.7 to 9.6±4.2. There were seven responders among the 18 patients, which yielded a 39% response rate.
CONCLUSION
ECT has a moderate but significant effect on tardive dystonia and dyskinesia.
背景
迟发性运动障碍和运动障碍是潜在的不可逆转的神经综合征。多个来源报道了电惊厥治疗（ECT）的成功案例；然而，现有的回顾性研究和开放性前瞻性试验提供的关于反应率的信息很少。
方法
18 名连续的迟发性运动障碍或运动障碍患者接受了标准的 ECT 疗程以治疗异常运动。在 ECT 疗程前后，使用不自主运动量表（AIMS）评估迟发性运动障碍和运动障碍的严重程度。AIMS 评分改善超过 50%的患者被归类为有反应者。
结果
平均 AIMS 评分从 19.1±4.7 降至 9.6±4.2。18 名患者中有 7 名有反应者，反应率为 39%。
结论
ECT 对迟发性运动障碍和运动障碍有中等但显著的疗效。
Zotero 插件