van Harten P N, Matroos G E, Hoek H W, Kahn R S
Psychiatric Hospital Welterhof, Heerlen, Netherlands.
Schizophr Res. 1996 May;19(2-3):195-203. doi: 10.1016/0920-9964(95)00096-8.
A prevalence study of extrapyramidal syndromes was conducted among all psychiatric inpatients of the Netherlands Antilles (n = 194; mean age 53.1). The Netherlands Antilles are very suitable for epidemiological research as it is a well-defined catchment area with only one psychiatric hospital and a health care system based on western principles. In this mainly chronic population, the prevalence was measured of tardive dystonia, tardive dyskinesia, parkinsonism and akathisia using respectively the Fahn-Marsden rating scale, the Abnormal Involuntary Movement Scale, the Unified Parkinson Disease Rating Scale and the Barnes Akathisia Rating Scale. The prevalence numbers were for tardive dystonia 13.4%, tardive dyskinesia 39.7%, parkinsonism 36.1%, akathisia 9.3% and pseudoakathisia 12.9%. The most important conclusions were: (1) The prevalence of tardive dystonia was higher than reported in most other studies and (2) extrapyramidal syndromes are very common in this predominantly Negroid population, with three out of four patients suffering of one or more extrapyramidal syndromes.
在荷属安的列斯群岛的所有精神科住院患者（n = 194；平均年龄53.1岁）中开展了一项锥体外系综合征患病率研究。荷属安的列斯群岛非常适合进行流行病学研究，因为它是一个界定明确的集水区，只有一家精神病医院且医疗保健系统基于西方原则。在这个主要为慢性患者的群体中，分别使用法恩-马斯登评定量表、异常不自主运动量表、统一帕金森病评定量表和巴恩斯静坐不能评定量表来测量迟发性肌张力障碍、迟发性运动障碍、帕金森综合征和静坐不能的患病率。迟发性肌张力障碍的患病率为13.4%，迟发性运动障碍为39.7%，帕金森综合征为36.1%，静坐不能为9.3%，假性静坐不能为12.9%。最重要的结论是：（1）迟发性肌张力障碍的患病率高于大多数其他研究报告的结果；（2）锥体外系综合征在这个以黑人为主的群体中非常常见，四分之三的患者患有一种或多种锥体外系综合征。
