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儿童胰腺囊性畸胎瘤:临床表现、评估与管理

Childhood cystic teratoma of the pancreas: clinical presentation, evaluation and management.

作者信息

Wang Yi, Jin Shuguang, Wang Weiya, Lu Changli, Liu Rongbo, Zhong Lin, Li Yuan

机构信息

Department of Pediatric Surgery, West China Hospital of Sichuan University, Chengdu 610041, China.

Department of Pathology, West China Hospital of Sichuan University, Chengdu, China.

出版信息

Pancreatology. 2014 Jul-Aug;14(4):312-5. doi: 10.1016/j.pan.2014.03.021. Epub 2014 Apr 5.

DOI:10.1016/j.pan.2014.03.021
PMID:25062883
Abstract

Pancreatic cystic teratoma in children is extremely rare. Here we present a female infant with a mature cystic teratoma of the pancreatic body. The patient was admitted for a palpable abdominal mass and anorexia. Computed tomography (CT) indicated a huge cystic mass in the abdominal cavity. Exploratory laparotomy was performed, and the tumor was excised completely. Pathology confirmed the tumor was a mature cystic teratoma of pancreatic origin. Two months after the initial surgery, a pseudocyst was detected and then cystojejunostomy was performed. Fourteen months after the second surgery, tumor relapse occurred and distal pancreatectomy was performed. The patient remained well without tumor recurrence during the next 24 months of follow-up. Our experience suggests that clinical manifestations of children with pancreatic cystic teratomas might be nonspecific and preoperative diagnosis is difficult. Radical tumor resection and maximized preservation of healthy pancreatic tissue should always be balanced in surgical treatment.

摘要

儿童胰腺囊性畸胎瘤极为罕见。在此,我们报告一名患有胰体成熟囊性畸胎瘤的女婴。该患者因可触及的腹部肿块及厌食入院。计算机断层扫描(CT)显示腹腔内有一个巨大的囊性肿块。进行了剖腹探查术,并将肿瘤完全切除。病理证实该肿瘤为胰腺来源的成熟囊性畸胎瘤。初次手术后两个月,发现一个假性囊肿,随后进行了囊肿空肠吻合术。第二次手术后14个月,肿瘤复发,遂进行了胰腺远端切除术。在接下来24个月的随访中,患者情况良好,无肿瘤复发。我们的经验表明,胰腺囊性畸胎瘤患儿的临床表现可能不具有特异性,术前诊断困难。在手术治疗中,应始终平衡肿瘤的根治性切除与健康胰腺组织的最大程度保留。

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