Corrigall W A, Coen K M
Addiction Research Foundation, Toronto, Ontario, Canada.
Psychopharmacology (Berl). 1989;99(1):136-9. doi: 10.1007/BF00634468.
The practicality of using second-order fixed-interval schedules in studies of heroin reinforcement with rats was examined. Optimum rates of responding were obtained with a dose of 0.03 mg/kg/infusion and an interval duration of 3 min. In addition, schedules consisting of a only a single interval were shown to be practical, leading to response rates comparable to those obtained with cocaine or food as reinforcer.
研究了在大鼠海洛因强化研究中使用二阶固定间隔时间表的实用性。在剂量为0.03毫克/千克/输注且间隔持续时间为3分钟的情况下获得了最佳反应率。此外，仅由单个间隔组成的时间表被证明是可行的，其反应率与以可卡因或食物作为强化物时获得的反应率相当。
