12 岁女孩对利多卡因过敏，但对阿替卡因耐受。
Anaphylaxis to lidocaine with tolerance to articaine in a 12 year old girl.
机构信息
Dental Department, King Khalid University Hospital, King Saud University, Saudi Arabia.
Dental Department, Ministry of Health, Saudi Arabia.
出版信息
Saudi Pharm J. 2014 Jul;22(3):280-2. doi: 10.1016/j.jsps.2013.10.001. Epub 2013 Oct 12.
True allergic reactions to local anesthetics are extremely rare and constitute less than 1% of all reactions. In addition, many of those allergic reactions are caused by the preservative constituents of the local anesthetics. Here we report a 12 year old girl with anaphylaxis to lidocaine (an amide local anesthetic) on two occasions. The allergy was confirmed by positive skin prick test to the drug. Skin testing and challenge to another amide local anesthetic (articaine) were negative. Subsequently, its use was well tolerated in a dental procedure. Up to our knowledge, this is the first report of a patient who is allergic to lidocaine and tolerant to articaine.
真正对局部麻醉剂的过敏反应极为罕见，不到所有反应的 1%。此外，许多过敏反应是由局部麻醉剂的防腐剂成分引起的。在这里，我们报告了一例 12 岁女孩在两次情况下对利多卡因（酰胺类局部麻醉剂）发生过敏反应的病例。该过敏反应通过对该药物的皮肤点刺试验得到确认。皮肤试验和对另一种酰胺类局部麻醉剂（阿替卡因）的挑战呈阴性。随后，在牙科手术中使用时耐受性良好。据我们所知，这是首例对利多卡因过敏但对阿替卡因耐受的患者报告。
Zotero 插件