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阿替卡因作为利多卡因过敏的替代药物:一名70岁男性患者的病例报告

Articaine as an alternative in lidocaine allergy: Case report of a seventy year old male patient.

作者信息

Dey Mansi, Mishra Bibhu Prasad, Awasthi Deepti, Sahoo Abhijeeta

机构信息

Oral and Maxillofacial Surgery, ITS Centre for Dental Studies and Research, Muradnagar, Ghaziabad, Uttar Pradesh, India.

Oral and Maxillofacial Surgery, ITS Centre for Dental Studies and Research, Greater Noida, Uttar Pradesh, India.

出版信息

Int J Surg Case Rep. 2020;77:941-943. doi: 10.1016/j.ijscr.2020.11.044. Epub 2020 Nov 11.

Abstract

INTRODUCTION

Allergy to lidocaine is extremely rare but if it occurs, one should switch to an alternative drug and discontinue the use of lidocaine so that adverse consequences do not occur.

PRESENTATION OF CASE

We present the case of a 70 year old male patient who had come to our department to undergo extraction of his decayed teeth under local anesthesia.

DISCUSSION

He had history of allergy to lidocaine. Type IV hypersensitivity to lidocaine was confirmed by positive skin prick testing to the drug. Skin prick testing was also performed for articaine that was available with us, and the test was found to be negative without any wheal or flare reaction even after 72 h. Thus it was confirmed that he was non-allergic to articaine and successfully underwent exodontia by using the same.

CONCLUSION

Articaine can be a suitable alternative in patients with true lignocaine allergy and vice-versa. No cross-reactivity has been reported between lidocaine and articaine so far. However, the number of cases reported in the past are limited, hence more cases are required in the future to prove its authenticity.

摘要

引言

利多卡因过敏极为罕见,但一旦发生,应改用其他药物并停用利多卡因,以免出现不良后果。

病例介绍

我们报告一例70岁男性患者,他到我们科室接受局部麻醉下的龋齿拔除术。

讨论

他有对利多卡因过敏的病史。通过对该药物的皮肤点刺试验呈阳性,证实对利多卡因存在IV型超敏反应。我们还对可用的阿替卡因进行了皮肤点刺试验,即使在72小时后,试验结果仍为阴性,未出现任何风团或红晕反应。因此,证实他对阿替卡因不过敏,并使用阿替卡因成功进行了拔牙术。

结论

对于真正对利多卡因过敏的患者,阿替卡因可能是一种合适的替代药物,反之亦然。迄今为止,尚未报道利多卡因和阿替卡因之间存在交叉反应。然而,过去报道的病例数量有限,因此未来需要更多病例来证明其真实性。

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