Gore J M, Thompson M J, Becker R C
Department of Medicine, University of Massachusetts Medical School, Worcester.
Chest. 1989 Oct;96(4):939-41. doi: 10.1378/chest.96.4.939.
A case of massive pulmonary embolism complicated by acute cor pulmonale and shock is presented. The IV administration of recombinant tissue-type plasminogen activator (rt-PA) was associated with prompt reversal of clinical, ECG, and nuclear radiographic findings. The role of thrombolytic therapy with rt-PA for massive pulmonary embolism associated with hemodynamic decompensation deserves further investigation.
本文报告一例大面积肺栓塞合并急性肺心病和休克的病例。静脉注射重组组织型纤溶酶原激活剂（rt-PA）后，临床、心电图和核素影像学表现迅速逆转。rt-PA溶栓治疗在伴有血流动力学代偿失调的大面积肺栓塞中的作用值得进一步研究。
