基于免疫的干预措施以预防产后 HIV-1 传播。

Immune-based interventions to prevent postnatal HIV-1 transmission.

机构信息

Department of Pediatrics and Human Vaccine Institute, Duke University Medical Center, Durham, NC 27705, USA.

出版信息

Trends Microbiol. 2014 Aug;22(8):425-7. doi: 10.1016/j.tim.2014.04.009.

DOI:10.1016/j.tim.2014.04.009

Abstract

Despite global scale-up in antiretroviral-based prevention of mother-to-child transmission services, more than 250 000 infants become infected with HIV-1 each year. Breast milk transmission is responsible for almost half of these infections. The development of alternative strategies to prevent postnatal HIV-1 transmission is imperative to achieve a generation free of HIV-1.

摘要

尽管在全球范围内扩大了基于抗逆转录病毒的母婴传播预防服务，但每年仍有超过 25 万名婴儿感染 HIV-1。母乳传播是造成这些感染的近一半原因。必须开发替代策略来预防产后 HIV-1 传播，以实现无 HIV-1 的一代。