移植后糖耐量受损和新发糖尿病中与β细胞糖毒性相关的单核苷酸多态性 - Suppr

β cell glucotoxic-associated single nucleotide polymorphisms in impaired glucose tolerance and new-onset diabetes after transplantation.

作者信息

Chand Sourabh, Shabir Shazia, Chan Winnie, McCaughan Jennifer A, McKnight Amy Jayne, Maxwell Alexander P, Borrows Richard

机构信息

1 Department of Nephrology and Kidney Transplantation Queen Elizabeth Hospital Birmingham, United Kingdom 2 Centre for Translational Inflammation Research, University of Birmingham Birmingham, United Kingdom 3 Regional Nephrology Unit Belfast City Hospital Belfast, Northern Ireland.

出版信息

Transplantation. 2014 Aug 15;98(3):e19-20. doi: 10.1097/TP.0000000000000268.

DOI:10.1097/TP.0000000000000268

PMID:25089340

Abstract

摘要

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β cell glucotoxic-associated single nucleotide polymorphisms in impaired glucose tolerance and new-onset diabetes after transplantation.移植后糖耐量受损和新发糖尿病中与β细胞糖毒性相关的单核苷酸多态性

Transplantation. 2014 Aug 15;98(3):e19-20. doi: 10.1097/TP.0000000000000268.

Association of the PCK2 Gene Polymorphism With New-onset Glucose Intolerance in Japanese Kidney Transplant Recipients.日本肾移植受者中PCK2基因多态性与新发葡萄糖不耐受的关联

Transplant Proc. 2018 May;50(4):1045-1049. doi: 10.1016/j.transproceed.2018.01.042.

Single-nucleotide polymorphisms in P450 oxidoreductase and peroxisome proliferator-activated receptor-α are associated with the development of new-onset diabetes after transplantation in kidney transplant recipients treated with tacrolimus.细胞色素 P450 氧化还原酶和过氧化物酶体增殖物激活受体-α 的单核苷酸多态性与接受他克莫司治疗的肾移植受者移植后新发糖尿病的发生有关。

Pharmacogenet Genomics. 2013 Dec;23(12):649-57. doi: 10.1097/FPC.0000000000000001.

Significant associations between CCL5 gene polymorphisms and post-transplantational diabetes mellitus in Korean renal allograft recipients.CCL5 基因多态性与韩国肾移植受者移植后糖尿病的显著相关性。

Am J Nephrol. 2010;32(4):356-61. doi: 10.1159/000319704. Epub 2010 Aug 31.

Genetic polymorphisms of the transcription factor NFATc4 and development of new-onset diabetes after transplantation in Hispanic kidney transplant recipients.转录因子 NFATc4 的遗传多态性与西班牙裔肾移植受者移植后新发糖尿病的发生。

Transplantation. 2012 Feb 15;93(3):325-30. doi: 10.1097/TP.0b013e31823f7f26.

Hypoadiponectinemia is associated with insulin resistance and glucose intolerance after renal transplantation: impact of immunosuppressive and antihypertensive drug therapy.低脂联素血症与肾移植术后胰岛素抵抗和葡萄糖耐量异常相关：免疫抑制和抗高血压药物治疗的影响

Clin J Am Soc Nephrol. 2006 May;1(3):575-82. doi: 10.2215/CJN.01471005. Epub 2006 Mar 22.

Pancreatic iron and glucose dysregulation in thalassemia major.地中海贫血症中的胰腺铁和葡萄糖失调。

Am J Hematol. 2012 Feb;87(2):155-60. doi: 10.1002/ajh.22223. Epub 2011 Nov 24.

Hypertriglyceridaemic waist phenotype and β-cell function in subjects with normal and impaired glucose tolerance.在糖耐量正常和受损的受试者中，高甘油三酯血症性腰围表型与β细胞功能。

Diabet Med. 2011 Oct;28(10):1229-33. doi: 10.1111/j.1464-5491.2011.03332.x.

Association of TCF7L2 polymorphism with diabetes mellitus, metabolic syndrome, and markers of beta cell function and insulin resistance in a population-based sample of Emirati subjects.在基于人群的阿联酋受试者样本中，TCF7L2基因多态性与糖尿病、代谢综合征以及β细胞功能和胰岛素抵抗标志物的关联。

Diabetes Res Clin Pract. 2008 Jun;80(3):392-8. doi: 10.1016/j.diabres.2008.01.008. Epub 2008 Feb 20.

Posttransplant diabetes mellitus after renal transplantation in Korea.

Transplant Proc. 1996 Jun;28(3):1159-60.

引用本文的文献

Pharmacogenetics of posttransplant diabetes mellitus.移植后糖尿病的药物遗传学

Pharmacogenomics J. 2017 Jun;17(3):209-221. doi: 10.1038/tpj.2017.1. Epub 2017 Mar 28.

Classification of Kidney Transplant Recipients Using a Combination of Estimated GFR and Albuminuria Reflects Risk.使用估算肾小球滤过率和蛋白尿的组合对肾移植受者进行分类可反映风险。

Transplant Direct. 2016 Jul 25;2(8):e96. doi: 10.1097/TXD.0000000000000606. eCollection 2016 Aug.

Analysis of single nucleotide polymorphisms implicate mTOR signalling in the development of new-onset diabetes after transplantation.单核苷酸多态性分析表明，mTOR信号传导与移植后新发糖尿病的发生有关。

BBA Clin. 2016 Jan 8;5:41-5. doi: 10.1016/j.bbacli.2015.12.004. eCollection 2016 Jun.

CRTC2 polymorphism as a risk factor for the incidence of metabolic syndrome in patients with solid organ transplantation.CRTC2基因多态性作为实体器官移植患者代谢综合征发病的危险因素。

Pharmacogenomics J. 2017 Jan;17(1):69-75. doi: 10.1038/tpj.2015.82. Epub 2015 Dec 8.

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β cell glucotoxic-associated single nucleotide polymorphisms in impaired glucose tolerance and new-onset diabetes after transplantation.

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