炎性视神经病变
Inflammatory optic neuropathies.
作者信息
Costello Fiona
出版信息
Continuum (Minneap Minn). 2014 Aug;20(4 Neuro-ophthalmology):816-37. doi: 10.1212/01.CON.0000453316.60013.52.
PURPOSE OF REVIEW
The aim of this review is to highlight the clinical presentation of a variety of inflammatory optic neuropathies through a case-based format. While emphasis will be placed on optic neuritis, which represents the most common acquired inflammatory optic nerve injury, the cardinal clinical features of other demyelinating forms of optic neuropathy and potential mimics for typical optic neuritis will be discussed.
RECENT FINDINGS
Novel developments in the diagnostic evaluation, clinical associations, and treatment options for several inflammatory optic neuropathies will be described. Key points will emphasize clinical pearls and potential pitfalls that may thwart early diagnosis of underlying demyelinating, infectious, and inflammatory diseases presenting with optic nerve involvement.
SUMMARY
This review will aid the clinician in identifying potential red flags that should prompt consideration for causes of inflammatory optic nerve injury linked to neurologic and systemic disorders, and help guide safe and effective management for these conditions.
综述目的
本综述旨在通过基于病例的形式突出各种炎症性视神经病变的临床表现。虽然将重点关注视神经炎，其是最常见的获得性炎症性视神经损伤，但也将讨论其他脱髓鞘性视神经病变的主要临床特征以及典型视神经炎的潜在模仿者。
最新发现
将描述几种炎症性视神经病变在诊断评估、临床关联和治疗选择方面的新进展。关键点将强调可能阻碍对伴有视神经受累的潜在脱髓鞘性、感染性和炎症性疾病进行早期诊断的临床要点和潜在陷阱。
总结
本综述将帮助临床医生识别潜在的警示信号，这些信号应促使其考虑与神经和全身性疾病相关的炎症性视神经损伤的病因，并有助于指导对这些病症进行安全有效的管理。
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