Crespo-Leiro M G, Delgado-Jiménez J, López L, Alonso-Pulpón L, González-Vilchez F, Almenar-Bonet L, Rábago G, Pérez-Villa F, Paniagua Martín M J, Arizón Del Prado J M, Sousa-Casasnovas I, Manito-Lorite N, Díaz-Molina B, Pascual-Figal D, Lage-Galle E, Blasco-Peiró T, De la Fuente-Galán L, Muñiz J
Hospital Universitario A Coruña, La Coruña, Spain.
Clin Transplant. 2014 Oct;28(10):1142-7. doi: 10.1111/ctr.12432. Epub 2014 Oct 1.
A number of changes in the management of heart transplantation (HT) patients have each tended to reduce the risk of post-HT hematologic cancer, but little information is available concerning the overall effect on incidence in the HT population.
Comparison of data from the Spanish Post-Heart-Transplantation Tumour Registry for the periods 1991-2000 and 2001-2010.
The incidence among patients who underwent HT in the latter period was about half that observed in the former, with a particularly marked improvement in regard to incidence more than five yr post-HT.
Changes in HT patient management have jointly reduced the risk of hematologic cancer in the Spanish HT population. Long-term risk appears to have benefited more than short-term risk.
心脏移植(HT)患者管理方面的多项改变各自倾向于降低HT后血液系统癌症的风险,但关于对HT人群发病率的总体影响,可用信息很少。
比较西班牙心脏移植后肿瘤登记处1991 - 2000年和2001 - 2010年期间的数据。
后一时期接受HT的患者发病率约为前一时期观察到的一半,在HT后超过5年的发病率方面有特别显著的改善。
HT患者管理方面的改变共同降低了西班牙HT人群中血液系统癌症的风险。长期风险似乎比短期风险受益更多。