Howard James K, Amin Chintan, Lainhart Brendan, Smith Jason A, Rimington Jack, Hyland Christopher J T
School of Chemistry, University of Wollongong , Wollongong, New South Wales 2522, Australia.
J Org Chem. 2014 Sep 5;79(17):8462-8. doi: 10.1021/jo501423u. Epub 2014 Aug 22.
Nitrogen-substituted methylenecyclopropanes have been prepared by a strain-driven Overman rearrangement of cyclopropenylmethyl trichloroacetimidates. The reaction proceeds at room temperature and without the need of a transition-metal catalyst. Furthermore, it has been shown that C-3-substituted cyclopropenylmethyl trichloroacetimidates undergo a hydrolytic ring-opening reaction to form allenylcarbinols.
通过环丙烯基甲基三氯乙酰亚胺酯的应变驱动奥弗曼重排反应制备了氮取代的亚甲基环丙烷。该反应在室温下进行，无需过渡金属催化剂。此外，已表明C-3取代的环丙烯基甲基三氯乙酰亚胺酯会发生水解开环反应生成联烯基甲醇。
