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蝎毒素对正常及克氏锥虫感染大鼠肠嗜铬样细胞的影响:一项形态学研究

Effect of scorpion toxin on the enterochromaffin-like cells in normal and Trypanosoma cruzi-infected rats: a morphological study.

作者信息

Toppa N H, Leite V H, Barbosa A J, Chiari E, Gonzaga H M, Freire-Maia L, Cunha-Melo J R

出版信息

Rev Inst Med Trop Sao Paulo. 1989 Jan-Feb;31(1):7-13. doi: 10.1590/s0036-46651989000100002.

DOI:10.1590/s0036-46651989000100002
PMID:2510237
Abstract

Intravenous injection of scorpion toxin (Tityus serrulatus) in normal and Trypanosoma cruzi infected rats did not cause ultrastructural morphologic changes on enterochromaffin-like (ECL) cells of the stomach, although it induced a significant increase of the gastric secretion. Our data seem to indicate that gastric ECL cells structure is not affected by stimulation with scorpion toxin or by acute infection with T. cruzi in the rat.

摘要

对正常大鼠和感染克氏锥虫的大鼠静脉注射蝎毒素(锯齿脂鲤蝎),虽会显著增加胃酸分泌,但不会引起胃嗜铬样(ECL)细胞的超微结构形态变化。我们的数据似乎表明,大鼠胃ECL细胞的结构不受蝎毒素刺激或克氏锥虫急性感染的影响。

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