Caruso S, Sgolastra F, Gatto R
Department of Clinical Medicine, Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
Eur J Paediatr Dent. 2014 Jun;15(2):90-4.
In the last decade, tissue engineering has undergone enormous expansion in the fields of regenerative medicine and dentistry. In response to mechanical and chemical injuries, the dentine-pulp complex possesses a regenerative ability due to a speci?c population of mesenchymal stem cells, which have been widely described in literature. The postnatal dental pulp also contains progenitor stem cells that participate in dental regeneration. Knowledge of the regenerative potential of these cells is important in terms of understanding and applying their biological and chemical characteristics.
Through the isolation and exploration of the regenerative abilities of these stem cells, new therapeutic possibilities may be possible, opening the way for improving paediatric endodontic therapy.
在过去十年中,组织工程在再生医学和牙科领域得到了巨大的发展。牙本质-牙髓复合体在受到机械和化学损伤时,由于特定的间充质干细胞群而具有再生能力,这在文献中已有广泛描述。出生后的牙髓中也含有参与牙齿再生的祖干细胞。了解这些细胞的再生潜力对于理解和应用它们的生物学和化学特性非常重要。
通过分离和探索这些干细胞的再生能力,可能会有新的治疗可能性,为改善儿童牙髓治疗开辟道路。