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对患有注意力缺陷多动障碍的成年人执行功能进行细分。

Fractionating Executive Functions of Adults With ADHD.

作者信息

Bueno Viviane Freire, da Silva Maria Aparecida, Alves Tânia Maria, Louzã Mario Rodrigues, Pompéia Sabine

机构信息

1 Universidade Federal de São Paulo, Brazil.

2 Universidade de São Paulo, Brazil.

出版信息

J Atten Disord. 2017 Sep;21(11):944-955. doi: 10.1177/1087054714545537. Epub 2014 Aug 7.

Abstract

OBJECTIVE

To evaluate the performance of adults with ADHD considering the fractionation of executive functions into six different domains.

METHOD

Participants were adult ADHD patients who were not under the acute effects of medication ( n = 48). Their performance was compared with that of a healthy control group ( n = 20) of comparable age, education, and nonverbal intelligence quotient. The cognitive domains assessed were executive shifting, updating, inhibition of prepotent responses, dual-task performance, planning, and access to long-term memory. We also assessed the symptoms of inattention, hyperactivity/impulsivity, anxiety, and depression by validated questionnaires.

RESULTS

Compared with controls, patients reported more symptoms related to ADHD, anxiety and depression symptoms and were impaired in the shifting cost measure and phonemic fluency (measure of access to long-term memory).

CONCLUSION

ADHD in adults selectively impaired executive shifting and access to long-term memory, domains that may alter performance in a wide range of daily tasks.

摘要

目的

考虑将执行功能细分为六个不同领域,评估成人注意力缺陷多动障碍(ADHD)患者的表现。

方法

参与者为未受药物急性影响的成年ADHD患者(n = 48)。将他们的表现与年龄、教育程度和非言语智商相当的健康对照组(n = 20)进行比较。评估的认知领域包括执行转换、更新、抑制优势反应、双任务表现、计划以及长期记忆的提取。我们还通过经过验证的问卷评估了注意力不集中、多动/冲动、焦虑和抑郁症状。

结果

与对照组相比,患者报告了更多与ADHD、焦虑和抑郁症状相关的症状,并且在转换成本测量和语音流畅性(长期记忆提取的测量指标)方面受损。

结论

成人ADHD选择性地损害了执行转换和长期记忆的提取,这些领域可能会改变广泛日常任务中的表现。

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