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结核性脑膜炎:诊断与治疗挑战

Tuberculous meningitis: Diagnostic and therapeutic challenges.

作者信息

Chin Jerome H

机构信息

School of Public Health, University of California, Berkeley.

出版信息

Neurol Clin Pract. 2014 Jun;4(3):199-205. doi: 10.1212/CPJ.0000000000000023.

Abstract

Neurologists are often the first medical providers to evaluate patients with possible infectious meningitis. Knowledge of the clinical presentations and cerebrospinal fluid, microbiologic, and neuroimaging findings for different etiologies is essential to make a prompt diagnosis and initiate appropriate treatment. Tuberculosis is a common cause of meningitis in developing countries with a high prevalence of pulmonary tuberculosis. However, tuberculosis affects populations in every country and all neurologists need to be vigilant for possible cases of tuberculous meningitis presenting to their medical facilities. This article discusses the challenges of diagnosing and treating tuberculous meningitis and highlights recent advances in diagnostic technology.

摘要

神经科医生常常是首批评估可能患有感染性脑膜炎患者的医疗人员。了解不同病因的临床表现、脑脊液、微生物学及神经影像学检查结果,对于迅速做出诊断并启动恰当治疗至关重要。在肺结核高发的发展中国家,结核病是脑膜炎的常见病因。然而,结核病影响着每个国家的人群,所有神经科医生都需警惕其医疗机构中可能出现的结核性脑膜炎病例。本文探讨了结核性脑膜炎诊断和治疗方面的挑战,并着重介绍了诊断技术的最新进展。

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