Boey Gerald E, Wasilenchuk Jennifer L
*Both the authors are affiliated with the Arbutus Laser Centre, Vancouver, British Columbia, Canada.
Dermatol Surg. 2014 Sep;40(9):1004-9. doi: 10.1097/01.DSS.0000452628.99209.4f.
Previous clinical studies have investigated cryolipolysis for noninvasive reduction of fat in abdomens, outer thighs, flanks, and backs. This study investigated feasibility of cryolipolysis for inner thigh treatment.
This pilot study evaluated a cryolipolysis flat cup vacuum applicator for treatment of inner thigh fat.
A prototype vacuum applicator was used to treat n = 11 subjects in a single-side inner thigh study. Cryolipolysis treatment was delivered to the larger thigh while the contralateral thigh served as a control. Follow-ups were conducted at 8 and 16 weeks. Equalization treatments were subsequently delivered to the contralateral thigh. Safety was assessed by monitoring side effects and adverse events. Efficacy was evaluated by ultrasound imaging, clinical photography, and patient surveys.
Side effects were typical and resolved spontaneously. Efficacy was demonstrated with ultrasound measurements showing 83% of subjects attained some level of fat layer reduction. Normalized mean reduction in fat layer thickness was 20%, corresponding to 3.3 mm. Patient surveys revealed 91% were satisfied and 82% felt inner thigh cryolipolysis was comfortable. Clinical photographs revealed visible reduction in inner thigh contour after treatment.
This study demonstrates feasibility of safe and efficacious cryolipolysis treatment to the inner thigh.
以往的临床研究探讨了冷冻溶脂术用于无创减少腹部、大腿外侧、侧腹和背部脂肪的效果。本研究调查了冷冻溶脂术治疗大腿内侧脂肪的可行性。
本初步研究评估了一种冷冻溶脂扁平杯真空 applicator 用于治疗大腿内侧脂肪的效果。
在一项单侧大腿内侧研究中，使用一种原型真空 applicator 治疗了 n = 11 名受试者。对较大的大腿进行冷冻溶脂治疗，而对侧大腿作为对照。在第 8 周和第 16 周进行随访。随后对对照侧大腿进行同等治疗。通过监测副作用和不良事件评估安全性。通过超声成像、临床摄影和患者调查评估疗效。
副作用较为典型且可自行缓解。超声测量显示 83% 的受试者脂肪层有一定程度的减少，证实了疗效。脂肪层厚度的标准化平均减少量为 20%，相当于 3.3 毫米。患者调查显示 91% 的患者满意，82% 的患者感觉大腿内侧冷冻溶脂术操作舒适。临床照片显示治疗后大腿内侧轮廓明显改善。
本研究证明了冷冻溶脂术安全有效地治疗大腿内侧脂肪的可行性。
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