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二氧化碳点阵激光与脉冲染料激光对手术瘢痕预防效果的比较

A comparison of the scar prevention effect between carbon dioxide fractional laser and pulsed dye laser in surgical scars.

作者信息

Kim Dai Hyun, Ryu Hwa Jung, Choi Jae Eun, Ahn Hyo Hyun, Kye Young Chul, Seo Soo Hong

机构信息

*All the authors are affiliated with the Department of Dermatology, Korea University College of Medicine, Seoul, Korea.

出版信息

Dermatol Surg. 2014 Sep;40(9):973-8. doi: 10.1097/01.DSS.0000452623.24760.9c.

Abstract

BACKGROUND

The use of ablative lasers based on the fractional approach is a novel strategy for the treatment of postoperative and acne scars in addition to wrinkles.

OBJECTIVE

To evaluate and compare the efficacy of carbon dioxide ablative fractional laser (AFL) and the pulsed dye laser (PDL) for the improvement of surgical scars.

MATERIALS AND METHODS

Fourteen Korean patients with surgical scars were enrolled for this study. Half of each scar was treated with a 10,600-nm AFL and the contralateral half with the 595-nm PDL. For early intervention of the postoperative scar, the laser treatments were begun after 2 weeks from the Mohs micrographic surgery.

RESULTS

Both PDL and AFL produced statistically significant improvements. However, comparatively, there was no statistical difference between them. In each variable, AFL was more effective than PDL in the improvement of pliability and thickness. In contrast, PDL was superior to AFL in the improvement of vascularity and pigmentation.

CONCLUSION

Pulsed dye laser and AFL treatments for surgical scar provide significant improvement. Pulsed dye laser was more effective in color of scar compared with AFL, which showed marked improvement in the contour of scar. Overall improvement was not statistically different in the Vancouver Scar Scale.

摘要

背景

基于分次治疗方法的剥脱性激光是一种除治疗皱纹外,还可用于治疗术后瘢痕和痤疮瘢痕的新策略。

目的

评估和比较二氧化碳剥脱性分次激光(AFL)和脉冲染料激光(PDL)改善手术瘢痕的疗效。

材料和方法

本研究纳入了14例有手术瘢痕的韩国患者。每条瘢痕的一半用10600纳米的AFL治疗,对侧一半用595纳米的PDL治疗。对于术后瘢痕的早期干预,在莫氏显微外科手术后2周开始激光治疗。

结果

PDL和AFL均产生了具有统计学意义的改善。然而,相比之下,两者之间没有统计学差异。在各变量中,AFL在改善柔韧性和厚度方面比PDL更有效。相比之下,PDL在改善血管化和色素沉着方面优于AFL。

结论

脉冲染料激光和AFL治疗手术瘢痕均有显著改善。与AFL相比,脉冲染料激光在瘢痕颜色改善方面更有效,而AFL在瘢痕轮廓改善方面表现显著。在温哥华瘢痕量表中,总体改善无统计学差异。

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