肥胖：肥胖相关代谢综合征中的脑损伤
Obesity: cerebral damage in obesity-associated metabolic syndrome.
作者信息
Rusinek Henry, Convit Antonio
机构信息
New York University School of Medicine, 145 East 32nd Street, New York, NY 10013, USA.
1] New York University School of Medicine, 145 East 32nd Street, New York, NY 10013, USA. [2] Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Building 35, Orangeburg, NY 10962, USA.
出版信息
Nat Rev Endocrinol. 2014 Nov;10(11):642-4. doi: 10.1038/nrendo.2014.141. Epub 2014 Aug 12.
Abstract
The prevalence of the metabolic syndrome has increased in tandem with that of obesity. The metabolic syndrome is associated with structural and functional cerebral damage. A new study confirms the association between the metabolic syndrome and reduced brain volume in the absence of diabetes mellitus. Here, we highlight how vascular dysfunction potentially contributes to this brain damage.
摘要
代谢综合征的患病率与肥胖症的患病率同步上升。代谢综合征与大脑的结构和功能损伤有关。一项新研究证实，在无糖尿病的情况下，代谢综合征与脑容量减少之间存在关联。在此，我们着重探讨血管功能障碍可能如何导致这种脑损伤。
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