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Do the genes of the innate immune response contribute to neuroprotection in Drosophila?
J Innate Immun. 2015;7(1):3-10. doi: 10.1159/000365195. Epub 2014 Aug 9.
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Dnr1 mutations cause neurodegeneration in Drosophila by activating the innate immune response in the brain.
Proc Natl Acad Sci U S A. 2013 May 7;110(19):E1752-60. doi: 10.1073/pnas.1306220110. Epub 2013 Apr 23.
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Normal aging hyperactivates innate immunity and reduces the medical efficacy of minocycline in brain injury.
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Inflammation and susceptibility to neurodegeneration: the use of unbiased genetics to decipher critical regulatory pathways.
Neuroscience. 2009 Feb 6;158(3):1143-50. doi: 10.1016/j.neuroscience.2008.08.031. Epub 2008 Aug 27.
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ATM kinase inhibition in glial cells activates the innate immune response and causes neurodegeneration in Drosophila.
Proc Natl Acad Sci U S A. 2012 Mar 13;109(11):E656-64. doi: 10.1073/pnas.1110470109. Epub 2012 Feb 21.
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The use of as a model organism to study immune-nanotoxicity.
Nanotoxicology. 2019 May;13(4):429-446. doi: 10.1080/17435390.2018.1546413. Epub 2018 Nov 19.

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Cell-death induced immune response and coagulopathy promote cachexia in .
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SUMO conjugation regulates immune signalling.
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Innate immune responses to paraquat exposure in a Drosophila model of Parkinson's disease.
Sci Rep. 2019 Sep 3;9(1):12714. doi: 10.1038/s41598-019-48977-6.
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Insights from intoxicated Drosophila.
Alcohol. 2019 Feb;74:21-27. doi: 10.1016/j.alcohol.2018.03.004. Epub 2018 Mar 21.
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Inflammation-Induced, STING-Dependent Autophagy Restricts Zika Virus Infection in the Drosophila Brain.
Cell Host Microbe. 2018 Jul 11;24(1):57-68.e3. doi: 10.1016/j.chom.2018.05.022. Epub 2018 Jun 19.
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NF-κB Immunity in the Brain Determines Fly Lifespan in Healthy Aging and Age-Related Neurodegeneration.
Cell Rep. 2017 Apr 25;19(4):836-848. doi: 10.1016/j.celrep.2017.04.007.
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Insulin-like Signaling Promotes Glial Phagocytic Clearance of Degenerating Axons through Regulation of Draper.
Cell Rep. 2016 Aug 16;16(7):1838-50. doi: 10.1016/j.celrep.2016.07.022. Epub 2016 Aug 4.
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Nobel Parasites in the Kingdom of Invertebrates.
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Chasing flies because time flies.
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本文引用的文献

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How do immune cells support and shape the brain in health, disease, and aging?
J Neurosci. 2013 Nov 6;33(45):17587-96. doi: 10.1523/JNEUROSCI.3241-13.2013.
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The ubiquitin ligase parkin mediates resistance to intracellular pathogens.
Nature. 2013 Sep 26;501(7468):512-6. doi: 10.1038/nature12566. Epub 2013 Sep 4.
3
Dnr1 mutations cause neurodegeneration in Drosophila by activating the innate immune response in the brain.
Proc Natl Acad Sci U S A. 2013 May 7;110(19):E1752-60. doi: 10.1073/pnas.1306220110. Epub 2013 Apr 23.
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Of flies and men: insights on organismal metabolism from fruit flies.
BMC Biol. 2013 Apr 15;11:38. doi: 10.1186/1741-7007-11-38.
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Transcriptome Profiling Following Neuronal and Glial Expression of ALS-Linked SOD1 in Drosophila.
G3 (Bethesda). 2013 Apr 9;3(4):695-708. doi: 10.1534/g3.113.005850.
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TDP-43 loss-of-function causes neuronal loss due to defective steroid receptor-mediated gene program switching in Drosophila.
Cell Rep. 2013 Jan 31;3(1):160-72. doi: 10.1016/j.celrep.2012.12.014. Epub 2013 Jan 17.
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Molecular chaperones protect against JNK- and Nmnat-regulated axon degeneration in Drosophila.
J Cell Sci. 2013 Feb 1;126(Pt 3):838-49. doi: 10.1242/jcs.117259. Epub 2012 Dec 21.

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