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烧伤患者的肺栓塞,是否有基于证据的预防性建议?病例报告及文献综述

Pulmonary embolism in burns, is there an evidence based prophylactic recommendation? Case report and review of literature.

作者信息

Sebastian Raul, Ghanem Omar, DiRoma Frank, Milner Stephen M, Price Leigh A

机构信息

Johns Hopkins University School of Medicine, Johns Hopkins Burn Center, Baltimore, MD 21224, United States.

Medstar Union Memorial Hospital, Baltimore, MD 21218, United States.

出版信息

Burns. 2015 Mar;41(2):e4-7. doi: 10.1016/j.burns.2014.06.018. Epub 2014 Aug 10.

DOI:10.1016/j.burns.2014.06.018
PMID:25115669
Abstract

Burn patients exhibit an acquired hypercoagulable state with increased risk of venous thromboembolism. Currently, no randomized control study assessing the efficacy of chemical venous thromboembolism (VTE) prophylaxis in burn patients has been performed. We present a case of a morbidly (body mass index>54kg/m(2)) obese patient with 18% total body surface area (TBSA) burn who developed a VTE and a non-fatal submassive pulmonary embolus (PE). We will be reviewing the current consensus of venous thrombosis prophylaxis in burn patients and briefly discuss the treatment of PE in this population.

摘要

烧伤患者呈现出获得性高凝状态,静脉血栓栓塞风险增加。目前,尚未进行评估化学性静脉血栓栓塞(VTE)预防措施对烧伤患者疗效的随机对照研究。我们报告一例极度肥胖(体重指数>54kg/m²)、全身18%体表面积(TBSA)烧伤的患者,该患者发生了VTE和非致死性次大面积肺栓塞(PE)。我们将回顾目前烧伤患者静脉血栓形成预防的共识,并简要讨论该人群PE的治疗。

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