Papa L A, Saia J A, Chung E K
Heart Lung. 1978 Nov-Dec;7(6):1015-9.
A young individual who developed ventricular fibrillation following atrial fibrillation in the WPW syndrome is presented. The precise cardiac rhythm diagnosis is extremely important for proper management. When the QRS morphology is bizarre and the ventricular rate is very fast (200 to 300 b.p.m.) in atrial fibrillation, the WPW syndrome should be considered as the underlying disorder. Digitalis should be avoided in this circumstance because anomalous conduction may be accelerated by the drug, leading to deterioration of the clinical picture and even death. When an antiarrhythmic drug is to be used, intravenous lidocaine is the drug of choice. For the prophylactic measure, oral quinidine or procainamide is equally effective for atrial fibrillation with anomalous conduction in the WPW syndrome.
本文介绍了一名患有预激综合征(WPW综合征)的年轻人,其在房颤后发生了室颤。准确的心律诊断对于正确治疗极为重要。当房颤时QRS波形态怪异且心室率极快(200至300次/分钟)时,应考虑WPW综合征为潜在疾病。在这种情况下应避免使用洋地黄,因为该药物可能会加速异常传导,导致临床症状恶化甚至死亡。当需要使用抗心律失常药物时,静脉注射利多卡因是首选药物。对于预防措施,口服奎尼丁或普鲁卡因胺对于WPW综合征伴异常传导的房颤同样有效。