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阿卡波糖治疗晚发性倾倒综合征所致严重低血糖症。

Treatment with acarbose in severe hypoglycaemia due to late dumping syndrome.

作者信息

Wang Congcong, Pang Shuguang, Jiang Qiang, Duan Guanglan, Sun Yongmei, Li Mei

机构信息

Endocrinology Department, Jinan Central Hospital affiliated to Shandong University, Jinan, Shandong, China.

Endocrinology Department, Jinan Central Hospital affiliated to Shandong University, Jinan, Shandong, China and Jinan Central Hospital affiliated to Shandong University, Jinan, Shandong, China.

出版信息

West Indian Med J. 2013 Dec;62(9):861-3. doi: 10.7727/wimj.2012.266.

DOI:10.7727/wimj.2012.266
PMID:25117397
Abstract

Dumping syndrome is a serious complication that may occur after gastric surgery in approximately 10% of patients in the 1990s. With the increasing number of patients undergoing bariatric surgery, the incidence of dumping syndrome is likely to increase in recent years. It is necessary for clinicians to recognize the syndrome and master its management. We present a case of recurrent loss of consciousness, which was finally accurately diagnosed as late dumping syndrome twelve years after subtotal gastrectomy and successfully treated with acarbose. A 66-year old lean male was found unconscious repeatedly within one year, oral glucose tolerance tests performed before and after acarbose treatment verified the diagnosis of late dumping syndrome. Hypoglycaemia can damage the body in acute and chronic form. Acarbose can be used as a successful treatment modality for reactive hypoglycaemia due to late dumping syndrome by influencing the release of hormone.

摘要

倾倒综合征是一种严重的并发症,在20世纪90年代,约10%的胃手术后患者可能会出现。随着接受减肥手术的患者数量增加,近年来倾倒综合征的发病率可能会上升。临床医生有必要认识该综合征并掌握其治疗方法。我们报告一例反复意识丧失的病例,该病例在胃大部切除术后12年最终被准确诊断为晚期倾倒综合征,并通过阿卡波糖成功治疗。一名66岁的消瘦男性在一年内多次被发现昏迷,阿卡波糖治疗前后进行的口服葡萄糖耐量试验证实了晚期倾倒综合征的诊断。低血糖会以急性和慢性形式损害身体。阿卡波糖可通过影响激素释放,作为治疗晚期倾倒综合征所致反应性低血糖的成功治疗方式。

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