Sündermann Simon H, Gordic Sonja, Manka Robert, Cesarovic Nikola, Falk Volkmar, Maisano Francesco, Alkadhi Hatem
Division of Cardiovascular Surgery, University Hospital Zurich, Zurich, Switzerland.
Int J Cardiovasc Imaging. 2015 Jan;31(1):135-42. doi: 10.1007/s10554-014-0516-7. Epub 2014 Aug 15.
To investigate the use of computed tomography (CT) to measure the mitral valve annulus size before implantation of a percutaneous mitral valve annuloplasty device in an animal trial. Seven domestic pigs underwent CT before and after implantation of a Cardioband™ (a percutaneously implantable mitral valve annuloplasty device) with a second-generation 128-section dual-source CT machine. Implantation of the Cardioband™ was performed in a standard fashion according to a protocol. Animals were sacrificed afterwards and the hearts explanted. The Cardioband™ was found to be adequately implanted in all animals, with no anchor dehiscence and no damage of the circumflex artery (CX) or the coronary sinus (CS). The correct length of the band as chosen according to the length of the posterior mitral annulus measured in CT before implantation was confirmed in gross examination in all animals. The device did not result in a metal artifact-related degradation of image quality. The closest distance from the closest anchor to the CX was 2.1 ± 0.7 mm in diastole and 1.6 ± 0.5 mm systole. Mitral annulus distance to the CS was 6.4 ± 1.3 mm in diastole and 7.7 ± 1.1 mm in systole. CT visualization and measurement of the mitral valve annulus dimensions is feasible and can become the imaging method of choice for procedure planning of Cardioband™ implantations or other transcatheter mitral annuloplasty devices.
在动物试验中，研究在经皮二尖瓣环成形装置植入前使用计算机断层扫描（CT）测量二尖瓣环大小的情况。七只家猪在植入Cardioband™（一种可经皮植入的二尖瓣环成形装置）前后，使用第二代128层双源CT机进行CT检查。按照方案以标准方式植入Cardioband™。之后对动物实施安乐死并取出心脏。结果发现，所有动物体内的Cardioband™均植入到位，未出现锚定处裂开，也未对回旋支动脉（CX）或冠状窦（CS）造成损伤。在所有动物的大体检查中，均证实根据植入前CT测量的二尖瓣后环长度所选择的带的长度正确。该装置未导致与金属伪影相关的图像质量下降。在舒张期，最近的锚定处到CX的最远距离为2.1±0.7毫米，在收缩期为1.6±0.5毫米。二尖瓣环到CS的距离在舒张期为6.4±1.3毫米，在收缩期为7.7±1.1毫米。CT可视化和测量二尖瓣环尺寸是可行的，并且可以成为Cardioband™植入或其他经导管二尖瓣环成形装置手术规划的首选成像方法。
