Cobas b121型动脉血气分析仪pH、PCO₂、PO₂、Na⁺、K⁺检测方法性能验证
Validation of Method Performance of pH, PCO2, PO2, Na(+), K(+) of Cobas b121 ABG Analyser.
作者信息
Nanda Sunil Kumar, Ray Lopamudra, Dinakaran Asha
机构信息
Associate Professor, Department of Biochemistry, Pondicherry Institute of Medical Sciences, Affiliated to Pondicherry University , Ganapathichettikulam, Kalapet, Pondicherry, India .
Assistant Professor, Department of Biochemistry, Pondicherry Institute of Medical Sciences, Affiliated to Pondicherry University , Ganapathichettikulam, Kalapet, Pondicherry, India .
出版信息
J Clin Diagn Res. 2014 Jun;8(6):CC05-7. doi: 10.7860/JCDR/2014/9218.4442. Epub 2014 Jun 20.
INTRODUCTION
The introduction of a new method or new analyser is a common occurrence in clinical biochemistry laboratory. Blood gas measurements and electrolytes are often performed in Point-of-Care (POC) settings. When a new POC analyser is obtained, the performance of the analyser should be evaluated by comparison to the measurements with the reference analyser in the laboratory.
OBJECTIVES
Evaluation of method performance of pH, PCO2, PO2, Na(+), K(+) of cobas b121 ABG analyser.
MATERIALS & METHODS: The evaluation of method performance of pH, PO2, PCO2, Na(+), K(+) of cobas b121 ABG analyser was done by comparing the results of 50 patient samples run on cobas b121 with the results obtained from Rapid lab values (reference analyser). Correlation coefficient was calculated from the results obtained from both the analysers. Precision was calculated by running biorad ABG control samples.
RESULTS
The correlation coefficient values obtained for parameters were close to 1.0 indicating good correlation. The CV obtained for all the parameters were less than 5 indicating good precision.
CONCLUSION
The new ABG analyser, Cobas b121 correlated well with the reference ABG analyser (Rapid Lab) and could be used to run on patient samples.
引言
在临床生物化学实验室中，引入新方法或新分析仪是常有的事。血气测量和电解质检测通常在即时检验（POC）环境中进行。当获得一台新的POC分析仪时，应通过与实验室中的参考分析仪测量结果进行比较，来评估该分析仪的性能。
目的
评估 cobas b121 血气分析仪的pH、PCO2、PO2、Na(+)、K(+)的方法性能。
材料与方法
通过比较在cobas b121上检测的50份患者样本结果与从快速实验室值（参考分析仪）获得的结果，来评估cobas b121血气分析仪的pH、PO2、PCO2、Na(+)、K(+)的方法性能。根据两台分析仪获得的结果计算相关系数。通过运行伯乐血气质控样本计算精密度。
结果
各参数获得的相关系数值接近1.0，表明相关性良好。所有参数获得的变异系数（CV）均小于5，表明精密度良好。
结论
新的血气分析仪Cobas b121与参考血气分析仪（快速实验室）相关性良好，可用于检测患者样本。
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