Zhang Yuhuan
School of Mathematics and Information Sciences, Henan University, Kaifeng 475004, China.
ScientificWorldJournal. 2014;2014:476912. doi: 10.1155/2014/476912. Epub 2014 Jul 8.
The paper investigates the observer design for a core circadian rhythm network in Drosophila and Neurospora. Based on the constructed highly nonlinear differential equation model and the recently proposed graphical approach, we design a rather simple observer for the circadian rhythm oscillator, which can well track the state of the original system for various input signals. Numerical simulations show the effectiveness of the designed observer. Potential applications of the related investigations include the real-world control and experimental design of the related biological networks.
本文研究了果蝇和脉孢菌中核心昼夜节律网络的观测器设计。基于构建的高度非线性微分方程模型和最近提出的图形方法,我们为昼夜节律振荡器设计了一个相当简单的观测器,它可以很好地跟踪各种输入信号下原系统的状态。数值模拟表明了所设计观测器的有效性。相关研究的潜在应用包括相关生物网络的实际控制和实验设计。